أعرض في EDS

Thermoanalytical and Microscopic Investigation of Interaction between Paracetamol and Fatty Acid Crystals

التفاصيل البيبلوغرافية
العنوان: Thermoanalytical and Microscopic Investigation of Interaction between Paracetamol and Fatty Acid Crystals
المؤلفون: A. K. Misra, G. M. Panpalia, Manju Misra, A. K. Dorle
المصدر: Journal of Macromolecular Science, Part A. 44:685-690
بيانات النشر: Informa UK Limited, 2007.
سنة النشر: 2007
مصطلحات موضوعية: chemistry.chemical_classification, Polymers and Plastics, Scanning electron microscope, Analytical chemistry, Infrared spectroscopy, Fatty acid, General Chemistry, Differential scanning calorimetry, chemistry, Saturated fatty acid, Materials Chemistry, Ceramics and Composites, Molecule, Fourier transform infrared spectroscopy, Thermal analysis, Nuclear chemistry
الوصف: The objective of this study was to investigate the possibility of interaction between paracetamol and saturated fatty acids. Although literature is replete with the interaction study of fatty acids with different drugs, few have examined the interaction with NSAIDs. Keeping in view the crystalline nature of paracetamol and fatty acids and to provide the intimate contact between the interacting molecules, crystals of binary mixture of drug with fatty acids were prepared by the solvent evaporation method. These crystals were subjected to FT‐IR, DSC, XRD, optical microscopy, SEM and AFM. DSC and XRD studies were unable to detect any interaction. Some changes were observed in FT‐IR spectrum of a binary mixture of drug with fatty acid. A better probe into interaction was obtained by microscopic techniques, especially atomic force microscopy.
تدمد: 1520-5738
1060-1325
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b6b842087895c0f58552a0b7e52038ba
https://doi.org/10.1080/10601320701351177
رقم الأكسشن: edsair.doi...........b6b842087895c0f58552a0b7e52038ba
قاعدة البيانات: OpenAIRE
الوصف
تدمد:15205738
10601325