Chemical investigation of the EtOAc extract of the medicinal plant Thymelaea lythroides yielded eight secondary metabolites, including bassiatin ( 1 ), daphenone ( 2 ), daphnelone ( 3 ), daphnoretin ( 4 ), δ -sesamin ( 5 ), wikstromol ( 6 ), trans -tiliroside ( 7 ), and rutarensin ( 8 ). The structures of the isolated compounds were determined on the basis of 1D and 2D NMR spectroscopy as well as mass spectrometry. Compounds 1 – 8 were reported from T. lythroides for the first time and the chemotaxonomic significance of these compounds is summarized.
