This paper reviews some papers discussing the effect of radio frequency (RF) on human cells and proposal toward better experimental work. A prototype of radio frequency absorber box with air ventilation was introduced in order to investigate its effect on human cells. A few factors that contribute to the effect of radiation is recognized and studied. The success of our proposed iron mesh box to absorb RF signals was demonstrated wherein normal level of RF radiation is achieved within the closed system of the incubator. The mesh box has been shown to have absorbed at least 88.11% of total RF generated.