Association between anemia and frailty in 13,175 community-dwelling older adults in China

التفاصيل البيبلوغرافية
العنوان: Association between anemia and frailty in 13,175 community-dwelling older adults in China
المؤلفون: Ye Ruan, Yanfei Guo, Paul Kowal, Ye Lu, Chazhen Liu, Shuangyuan Sun, Zhezhou Huang, Yang Zheng, Wenjing Wang, Gan Li, Yan Shi, Fan Wu
بيانات النشر: Research Square Platform LLC, 2019.
سنة النشر: 2019
الوصف: Background Anemia and frailty contribute to poor health outcomes in older adults; however, most current research in lower income countries has concentrated on anemia or frailty alone rather than in combination. The aim of the present study was to investigate the association between anemia and frailty in community-dwelling adults aged 50 years and older in China. Methods The study population was sourced from the 2007/10 SAGE China Wave 1. Anemia was defined as hemoglobin less than 13g/dL for men and less than 12g/dL for women. A frailty index (FI) was compiled to assess frailty. The association between anemia and frailty was evaluated using a 2-level hierarchical logistic model. Results The prevalence of anemia was 31.0% (95%CI: 28.4%, 33.8%) and frailty 14.7% (95%CI: 13.5%, 16.0%). In the univariate regression model, presence of anemia was significantly associated with frailty (OR=1.62, 95% CI: 1.39, 1.90) and the effect remained consistent after adjusting for various potential confounding factors including age, sex, education, household wealth, residence, smoking, alcohol drinking (adjusted OR =1.31, 95% CI:1.09, 1.57). In the linear model, each 1 g/dL increase in hemoglobin concentration was associated with 4% decrease in the odds of frailty after adjusting for several confounding variables (adjusted OR =0.96, 95% CI: 0.93, 0.99). Conclusion Anemia and low hemoglobin concentrations were significantly associated with frailty. Therefore, health care professionals caring for older adults should increase screening, assessment of causes and treatment of anemia as one method of avoiding, delaying or even reversing frailty.
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b9590bb6a3a0310e2bd9716f0ed3252b
https://doi.org/10.21203/rs.2.13089/v1
حقوق: OPEN
رقم الأكسشن: edsair.doi...........b9590bb6a3a0310e2bd9716f0ed3252b
قاعدة البيانات: OpenAIRE