Heart rate characteristic based modelling of atrial fibrillatory rate using implanted cardiac monitor data
| العنوان: | Heart rate characteristic based modelling of atrial fibrillatory rate using implanted cardiac monitor data |
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| المؤلفون: | Javier Saiz-Vivo, Mostafa Abdollahpur, Luca T Mainardi, Valentina D A Corino, Mirko De Melis, Robert Hatala, Frida Sandberg |
| المصدر: | Physiological Measurement. 44:035007 |
| بيانات النشر: | IOP Publishing, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Physiology, Physiology (medical), Biomedical Engineering, Biophysics |
| الوصف: | Objective. The objective of the present study is to investigate the feasibility of using heart rate characteristics to estimate atrial fibrillatory rate (AFR) in a cohort of atrial fibrillation (AF) patients continuously monitored with an implantable cardiac monitor. We will use a mixed model approach to investigate population effect and patient specific effects of heart rate characteristics on AFR, and will correct for the effect of previous ablations, episode duration, and onset date and time. Approach. The f-wave signals, from which AFR is estimated, were extracted using a QRST cancellation process of the AF episodes in a cohort of 99 patients (67% male; 57 ± 12 years) monitored for 9.2(0.2–24.3) months as median(min-max). The AFR from 2453 f-wave signals included in the analysis was estimated using a model-based approach. The association between AFR and heart rate characteristics, prior ablations, and episode-related features were modelled using fixed-effect and mixed-effect modelling approaches. Main results. The mixed-effect models had a better fit to the data than fixed-effect models showing h.c. of determination (R2 = 0.49 versus R2 = 0.04) when relating the variations of AFR to the heart rate features. However, when correcting for the other factors, the mixed-effect model showed the best fit (R2 = 0.04). AFR was found to be significantly affected by previous catheter ablations (p < 0.05), episode duration (p < 0.05), and irregularity of the RR interval series (p < 0.05). Significance. Mixed-effect models are more suitable for AFR modelling. AFR was shown to be faster in episodes with longer duration, less organized RR intervals and after several ablation procedures. |
| تدمد: | 1361-6579 0967-3334 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::bc41a5832e2e75d0d7e156d19798b8b3 https://doi.org/10.1088/1361-6579/acbc08 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........bc41a5832e2e75d0d7e156d19798b8b3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13616579 09673334 |
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