53 Cognitive Decline, Dementia and Air Pollution: A Report by the Committee on the Medical Effects of Air Pollutants
| العنوان: | 53 Cognitive Decline, Dementia and Air Pollution: A Report by the Committee on the Medical Effects of Air Pollutants |
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| المؤلفون: | Robert Maynard, Roxana Carare, Jonathan Grigg, Nick Fox, Seth Love, Ian Mudway, Gavin Shaddick, Juana Maria Delgado-Saborit, Valentina Guercio, Naomi Earl, Christina Mitsakou, Artemis Doutsi, Karen Exley, Sarah Robertson, Philippa Douglas, Alison Gowers |
| المصدر: | Annals of Work Exposures and Health. 67:i80-i81 |
| بيانات النشر: | Oxford University Press (OUP), 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Public Health, Environmental and Occupational Health |
| الوصف: | Dementia is an umbrella term for a range of conditions that affect how the brain works and, in particular, the ability to remember, think and reason. It mainly affects older people, both men and women, and gets worse over time. In recent years, there has been growing interest in the possibility that exposure to outdoor air pollution could increase the risk of dementia. COMEAP reviewed epidemiological and experimental studies and concluded that it is likely that air pollution contributes to a decline in mental ability and dementia in older people. The most likely way this occurs is through effects on the circulatory system. It is known that air pollutants, particularly fine particles, can affect the heart and blood vessels, including those of the brain. These effects are linked to vascular dementia, which is caused by damage to the blood vessels in the brain. Experimental studies suggest that air pollution may also stimulate immune cells in the brain, which can then damage nerve cells. It is also likely that some nano-sized (ultrafine) particles can enter the brain, either by transport along the olfactory nerve or by entering the circulation and crossing the blood-brain barrier. These particles may cause direct damage. Nonetheless, based on the available evidence, it does not seem likely that this is an important mechanism for the development of dementia. Recommendations were made for further research which would help develop the evidence on this important topic. |
| تدمد: | 2398-7316 2398-7308 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c60dde5a22f2ab1d09d8a435ffc2edf1 https://doi.org/10.1093/annweh/wxac087.196 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........c60dde5a22f2ab1d09d8a435ffc2edf1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23987316 23987308 |
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