Prediction of intradialytic hypotension using pre-dialysis features – a deep learning-based artificial intelligence model
العنوان: | Prediction of intradialytic hypotension using pre-dialysis features – a deep learning-based artificial intelligence model |
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المؤلفون: | Hanbi Lee, Sung Joon Moon, Sung Woo Kim, Ji Won Min, Hoon Suk Park, Hye Eun Yoon, Young Soo Kim, Hyung Wook Kim, Chul Woo Yang, Sungjin Chung, Eun Sil Koh, Byung Ha Chung |
المصدر: | Nephrology Dialysis Transplantation. |
بيانات النشر: | Oxford University Press (OUP), 2023. |
سنة النشر: | 2023 |
مصطلحات موضوعية: | Transplantation, Nephrology |
الوصف: | Background Intradialytic hypotension (IDH) is a serious complication of hemodialysis (HD) associated with increased risks of cardiovascular morbidity and mortality. However, its accurate prediction remains a clinical challenge. The aim of this study was to develop a deep learning–based artificial intelligence (AI) model to predict IDH using pre-dialysis features. Methods Data from 2,007 patients with 943,220 HD sessions at seven university hospitals were used. The performance of deep learning model was compared with 3 machine learning models (logistic regression, random forest, and XGBoost). Results IDH occurred in 5.39% of all studied HD sessions. A lower pre-dialysis blood pressure (BP), and a higher ultrafiltration (UF) target rate and interdialytic weight gain in IDH sessions compared to non-IDH sessions, and the occurrence of IDH in previous sessions was more frequent among IDH sessions compared to non-IDH sessions. Matthews correlation coefficient (MCC) and macro-averaged F1 score were used to evaluate both positive and negative prediction performances. Both values were similar in logistic regression, random forest, XGBoost, and deep learning models, developed with data from a single session. When combining data from the previous three sessions, the prediction performance of the deep learning model improved and became superior to that of other models. The common top-ranked features for IDH prediction were mean systolic BP (SBP) during the previous session, UF target rate, pre-dialysis SBP, and IDH experience during the previous session. Conclusions Our AI model predicts IDH accurately, suggesting it as a reliable tool for HD treatment. |
تدمد: | 1460-2385 0931-0509 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c9ffac4b87ef64c2dd3b979a2d94b8c9 https://doi.org/10.1093/ndt/gfad064 |
حقوق: | EMBARGO |
رقم الأكسشن: | edsair.doi...........c9ffac4b87ef64c2dd3b979a2d94b8c9 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 14602385 09310509 |
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