Measurements of hyperpolarized gas properties in the lung. part III:3HeT1
| العنوان: | Measurements of hyperpolarized gas properties in the lung. part III:3HeT1 |
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| المؤلفون: | L.W. Hedlund, X. J. Chen, Carey Mr, Harald E. Möller, Mark S. Chawla, C.T. Wheeler, G. A. Johnson |
| المصدر: | Magnetic Resonance in Medicine. 45:421-430 |
| بيانات النشر: | Wiley, 2001. |
| سنة النشر: | 2001 |
| مصطلحات موضوعية: | Cardiac output, business.industry, chemistry.chemical_element, Partial pressure, Oxygen, Nuclear magnetic resonance, Functional residual capacity, medicine.anatomical_structure, chemistry, medicine, Radiology, Nuclear Medicine and imaging, Limiting oxygen concentration, Hyperpolarization (physics), Respiratory system, Pulmonary alveolus, Nuclear medicine, business |
| الوصف: | Hyperpolarized (3)He spin-lattice relaxation was investigated in the guinea pig lung using spectroscopy and imaging techniques with a repetitive RF pulse series. T(1) was dominated by interactions with oxygen and was used to measure the alveolar O(2) partial pressure. In animals ventilated with a mixture of 79% (3)He and 21% O(2), T(1) dropped from 19.6 sec in vivo to 14.6 sec after cardiac arrest, reflecting the termination of the intrapulmonary gas exchange. The initial difference in oxygen concentration between inspired and alveolar air, and the temporal decay during apnea were related to functional parameters. Estimates of oxygen uptake were 29 +/- 11 mL min(-1) kg(-1) under normoxic conditions, and 9.0 +/- 2.0 mL min(-1) kg(-1) under hypoxic conditions. Cardiac output was estimated to be 400 +/- 160 mL min(-1) kg(-1). The functional residual capacity derived from spirometric magnetic resonance experiments varied with body mass between 5.4 +/- 0.3 mL and 10.7 +/- 1.1 mL. Magn Reson Med 45:421-430, 2001. |
| تدمد: | 1522-2594 0740-3194 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::c9ffbde09c5dc034c250a38d579961c2 https://doi.org/10.1002/1522-2594(200103)45:3<421::aid-mrm1055>3.0.co;2-k |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........c9ffbde09c5dc034c250a38d579961c2 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222594 07403194 |
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