Synthesis of Selenium-Containing Chitosan Derivatives and Their Antibacterial Activity
| العنوان: | Synthesis of Selenium-Containing Chitosan Derivatives and Their Antibacterial Activity |
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| المؤلفون: | A. R. Egorov, A. A. Artemjev, V. A. Kozyrev, D. N. Sikaona, V. V. Rubanik, I. S. Kritchenkov, N. Z. Yagafarov, O. M. Khubiev, T. A. Tereshina, E. K. Kultyshkina, B. Medjbour, V. N. Khrustalev, A. S. Kritchenkov |
| المصدر: | Applied Biochemistry and Microbiology. 58:132-135 |
| بيانات النشر: | Pleiades Publishing Ltd, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Applied Microbiology and Biotechnology, Biochemistry |
| الوصف: | Abstract The interaction of chitosan with 3-(chloromethyl)-[1,2,4]selendiazole[4,5-a]pyridin-4 bromide results in water-soluble, selenium-containing, cationic chitosan derivatives. Derivatives of chitosan with degrees of substitution of 0.15, 0.45, and 0.65 were obtained. These derivatives are characterized by a pronounced in vitro antibacterial activity against Staphylococcus aureus and Escherichia coli, and the antibacterial activity of the derivatives increases with an increase in their degree of substitution. The antibacterial activity of the highly substituted derivative is comparable to that of the conventional antibiotics ampicillin and gentamicin. |
| تدمد: | 1608-3024 0003-6838 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::d28ab27448056f6b5a673accf85749ab https://doi.org/10.1134/s0003683822020053 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........d28ab27448056f6b5a673accf85749ab |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16083024 00036838 |
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