Irreversible Electroporation For Hepatocellular Carcinoma: Longer-Term Outcomes At A Single Centre
| العنوان: | Irreversible Electroporation For Hepatocellular Carcinoma: Longer-Term Outcomes At A Single Centre |
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| المؤلفون: | Helen Kavnoudias, William Kemp, Elliot Freeman, Ammar Majeed, Wa Cheung, Stuart K. Roberts |
| المصدر: | CardioVascular and Interventional Radiology. 44:247-253 |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Radiofrequency ablation, medicine.medical_treatment, Incidence (epidemiology), Microwave ablation, Irreversible electroporation, Liver transplantation, Ablation, medicine.disease, 030218 nuclear medicine & medical imaging, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, Hepatocellular carcinoma, medicine, Radiology, Nuclear Medicine and imaging, Radiology, Stage (cooking), Cardiology and Cardiovascular Medicine, business |
| الوصف: | Irreversible electroporation (IRE) is a non-thermal ablation technique for unresectable hepatocellular carcinoma (HCC) not amenable to standard thermal ablation. The aim of this study was to report our longer-term outcomes using this treatment modality. We identified all patients at our institution who underwent IRE for HCC between December 2008 and October 2019 as recommended after multi-disciplinary team review. Demographic, clinical, tumour response and survival data up until 1 March, 2020 were analysed. The primary outcome was local recurrence-free survival (LRFS) in patients who had a complete response (CR). Secondary outcomes included CR rates, procedure-related complications and the incidence of death or liver transplantation. A total of 23 patients (78% males, median age 65.2 years) received IRE therapy to 33 HCC lesions during the study period with the median tumour size being 2.0 cm (range 1.0–5.0 cm). Twenty-nine (87.9%) lesions were successfully ablated after one (n = 26) or two (n = 3) procedures. The median follow-up time for these lesions was 20.4 months. The median overall LRFS was 34.5 (95% CI 24.8 -) months with a 6- and 12-month LRFS of 87.9% (95% CI 75.8–100) and 83.6% (95% CI 70.2–99.7), respectively. Tumours |
| تدمد: | 1432-086X 0174-1551 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::dc25a3c079d25c1c8a6c66231a458b3c https://doi.org/10.1007/s00270-020-02666-4 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........dc25a3c079d25c1c8a6c66231a458b3c |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 1432086X 01741551 |
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