Objective: Restenosis after Percutaneous Coronary Intervention (PCI) is regarded as the result of a combination of various pathological events. The mechanisms are complex and not completely understood. This study aims to determine the correlation between the concentration of serum sulfatide and restenosis after PCI. Method: We studied 68 consecutive patients with CHD of single-vessel disease who successfully underwent PCI. All patients were evaluated by a follow-up angiography approximately 6.5 months after the PCI and were divided into two groups, the restenosis (20 patients) and the nonrestenosis (48 patients). We measured and compared serum sulfatide levels and conventional cardiovascular risk factors in those two groups. Result: The serum sulfatide concentration (18.73 ± 3.81 μmol/L) in the restenosis group was significantly higher than that (11.52 ± 3.37 μmol/L) in the nonrestenosis group (p
