Background：Pressure ulcer is a common complication of long-term bedridden patients, but current treatment strategies have limited efficacy for pressure ulcer. Case presentation：We present a 17-year-old man with unstageable pressure ulcer treated with three-dimensional conformal radiotherapy. We irradiate the posterior lumbosacral pressure ulcer with 3D-CRT using a 6 MV photon beam. The patient was placed in a prone position and a total dose of 50cGy was administered. Then, the healing was evaluated using PUSH scale score on days 8，12 and 3 months after radiotherapy. After radiotherapy, beefy red tissue with a shiny, moist, granular appearance tissue are present in the wound bed, exudate amount was decreased, the depth of the pressure ulcer became significantly shallower and the wound surface area was reduced. PUSH scale score descreased from15 to 7.Conclusion: Radiotherapy could be a promising treatment strategy of unstageable pressure ulcer.
