Synthesis of pseudoboehmite-graphene oxide for drug delivery system

التفاصيل البيبلوغرافية
العنوان: Synthesis of pseudoboehmite-graphene oxide for drug delivery system
المؤلفون: Marcos Romero Filho, Leila Figueiredo de Miranda, Henrique de Arruda Kleist, Renato Meneghetti Peres, Bruno Sarmento, Maura Vincenza Rossi, Roberto Rodrigues Ribeiro, Guilherme Dias Moreno, Mariana Oliva de Oliveira, Antônio Hortêncio Munhoz Jr.
المصدر: Materials Today: Proceedings. 14:700-707
بيانات النشر: Elsevier BV, 2019.
سنة النشر: 2019
مصطلحات موضوعية: Drug, viruses, media_common.quotation_subject, Oxide, 02 engineering and technology, medicine.disease_cause, 01 natural sciences, law.invention, chemistry.chemical_compound, law, 0103 physical sciences, Medicine, media_common, 010302 applied physics, Hsv infection, business.industry, Graphene, Pseudoboehmite, 021001 nanoscience & nanotechnology, Virology, Bioavailability, Herpes simplex virus, chemistry, Drug delivery, 0210 nano-technology, business
الوصف: Pseudoboehmite is a hydrated aluminium compound produced by sol-gel process and used in drug delivery systems. The graphene oxide is a material that allows for many possibilities application as modify agent in a ceramic structure. The global prevalence and incidence of herpes simplex virus infections (HSV-1 and HSV-2) have risen worldwide. A big problem is that most persons with genital HSV infection have not received a diagnosis. Other concerning situation is that the herpes infected patients are more susceptible to HIV infections. It is also observed that in women the HSV infection are more common than in men. Acyclovir is an efficient drug for the treatment of herpes viruses. However, the oral bioavailability of acyclovir is limited due to varying and incomplete absorption. In this work, pseudoboehmite was produced with incorporation of graphene oxide in the gel. The pseudoboehmite-graphene oxide was used in in vitro drug delivery system for acyclovir.
تدمد: 2214-7853
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6155a158d1dec65ebad9f415ae616d3
https://doi.org/10.1016/j.matpr.2019.02.009
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........e6155a158d1dec65ebad9f415ae616d3
قاعدة البيانات: OpenAIRE