POS0132 THE FIRST ALGORITHM TO INTEGRATE ULTRASONOGRAPHY IN THE DIAGNOSTIC PROCESS OF DIFFERENTIAL DIAGNOSIS OF INFLAMMATORY ARTHROPATHY IN CLINICAL PRACTICE: A STUDY FROM THE MSUS WORKING GROUP OF THE ITALIAN SOCIETY OF RHEUMATOLOGY
| العنوان: | POS0132 THE FIRST ALGORITHM TO INTEGRATE ULTRASONOGRAPHY IN THE DIAGNOSTIC PROCESS OF DIFFERENTIAL DIAGNOSIS OF INFLAMMATORY ARTHROPATHY IN CLINICAL PRACTICE: A STUDY FROM THE MSUS WORKING GROUP OF THE ITALIAN SOCIETY OF RHEUMATOLOGY |
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| المؤلفون: | A. Damiani, G. Sakellariou, A. Adinolfi, C. A. Scirè, G. Pacini, E. Fiorentini, D. Carboni, S. Sirotti, P. Sarzi-Puttini, J. Madruga Dias, A. Iagnocco, G. Filippou |
| المصدر: | Annals of the Rheumatic Diseases. 81:292-293 |
| بيانات النشر: | BMJ, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Rheumatology, Immunology, Immunology and Allergy, General Biochemistry, Genetics and Molecular Biology |
| الوصف: | BackgroundMusculoskeletal ultrasonography (MSUS) is a useful tool for the diagnosis of several Rheumatic and Musculoskeletal Diseases (RMDs) but its role in the diagnostic pathways in clinical practice is still unclear as feasibility issues limit its application as a bed side technique.ObjectivesTo optimize the use of US in clinical practice, the MSUS Study Group of the Italian Society for Rheumatology aimed to develop an algorithm combining US with clinical and laboratory findings to improve the differential diagnosis among patients presenting with joint swelling.MethodsBased on a systematic literature review1 and experts’ opinion, MSUS Study Group Members attempt to identify a set of statements including the main US elementary lesions useful for US scanning in the suspicion of Rheumatoid arthritis (RA), Psoriatic arthritis (PsA), Rheumatic Polymyalgia (PMR), Gout, Calcium Pyrophosphate Deposition Disease (CPPD), Osteoarthritis (OA). Then, the MSUS Study Group defined through a survey and ranked in a 1000minds exercise the most important clinical/laboratory findings for the differential diagnosis of those diseases. Higher-ranked items were fitted in an algorithm driving the differential diagnosis of RMDs to a reduced spectrum of 2 to 4 possible diseases. Finally, the algorithm supported the performance of US according to the established scans for those specific diseases. To assess the algorithm’s performance, a pilot study was conducted on 59 patients, comparing the algorithm-based diagnosis with the final diagnosis based on rheumatologist’s experience and/or on classification criteria.ResultsSets of elementary US lesions and a scanning protocol for each included pathology were created (Table 1), optimized towards high sensibility and specificity. Among the findings evaluated, the age (Table 1.Elementary ultrasound lesions and joints to be scanned for each included pathologyDiseaseSites to scanUS elementary lesionsRAII-IV MCPsSynovial Hypertrophy (SH), Power Doppler (PD), erosionsWristV MTPPsAII-III MCPsPeritendonitisPIPsEnthesitisSoft tissue oedemaFlexor tendons of the handsTenosynovitisSoft tissue oedemaAchille’s tendon enthesisPD, erosionsProximal patellar tendon enthesisCPPDKnees (menisci and Hyaline Cartilage)CPP depositsWrist (triangular fibrocartilage complex)Any involved sitesCPP deposits, SH, PDGoutKneesDouble contour, tophiI MTPInvolved sitesSHPDOAInvolved sitesOsteophytesCartilage changesPMRShouldersBursitisArthritisRotator cuff integrityFigure 1.The final algorithmConclusionThe diagnostic algorithm produced in this pilot study correctly classified patients with the most prevalent RMDs in clinical practice. A longitudinal study on a large sample size is ongoing to evaluate the added value of US when implemented in this algorithm regarding diagnostic certainty, accuracy and early diagnosis.References[1]Sakellariou G, Scirè CA, Adinolfi A, Batticciotto A, Bortoluzzi A, Delle Sedie A, et al. Differential Diagnosis of Inflammatory Arthropathies by Musculoskeletal Ultrasonography: A Systematic Literature Review. Front Med. 7 maggio 2020;7:141.Disclosure of InterestsNone declared |
| تدمد: | 1468-2060 0003-4967 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ec3516eaf723fa26289fc7a1040e1f0c https://doi.org/10.1136/annrheumdis-2022-eular.3470 |
| رقم الأكسشن: | edsair.doi...........ec3516eaf723fa26289fc7a1040e1f0c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14682060 00034967 |
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