Risk assessment of in vitro cytotoxicity, antioxidant and antimicrobial activities of Mentha piperita L. essential oil
| العنوان: | Risk assessment of in vitro cytotoxicity, antioxidant and antimicrobial activities of Mentha piperita L. essential oil |
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| المؤلفون: | A M Fiorentini, K F Da Cunha, Natália Pontes Bona, Wyller Max Ferreira da Silva, Nathalia Stark Pedra, Alvaro Renato Guerra Dias, Francieli Moro Stefanello, Elessandra da Rosa Zavareze |
| المصدر: | Journal of Toxicology and Environmental Health, Part A. 85:230-242 |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Minimum bactericidal concentration, Antioxidant, ABTS, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Toxicology, medicine.disease_cause, Antimicrobial, law.invention, HaCaT, Minimum inhibitory concentration, chemistry.chemical_compound, chemistry, law, Staphylococcus aureus, medicine, Food science, Essential oil |
| الوصف: | The objective of this study was to determine the chemical composition as well as antioxidant, antibacterial, and cytotoxic properties of the essential oil of Mentha piperita L. (peppermint). Fifteen chemical constituents were identified in the essential oil, for a total of 99.99% of the compounds. The essential oil exhibited antimicrobial activity against two Gram-positive bacteria Staphylococcus aureus and Listeria monocytogenes. The minimum inhibitory concentration (MIC) of essential oil of Mentha piperita L. for Staphylococcus aureus and Listeria monocytogenes was 1.84 μg/ml, whereas the minimum bactericidal concentration (MBC) values were 3.7 and 7.43 μg/ml, respectively. The oil displayed potent antioxidant activity inhibiting up to approximately73% of 2,2'-azinothiobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals. In the cytotoxicity assay, the highest essential oil concentration (100 μg/ml) resulted in viability of approximately 90% human epidermal keratinocyte (HaCaT) cells. With respect to antitumor activity in C6 rat glioma cells, there was significant reduction in cell viability: 56-74% in 24 hr, and 71-77% in 48 hr. Data suggest that in presence of the essential oil of Mentha piperita L. antioxidant, antibacterial, antitumor and non-cytotoxic properties were noted. |
| تدمد: | 1087-2620 1528-7394 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ee41598874d892f943320aaf46860bb8 https://doi.org/10.1080/15287394.2021.1999875 |
| رقم الأكسشن: | edsair.doi...........ee41598874d892f943320aaf46860bb8 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 10872620 15287394 |
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