ChemInform Abstract: Azide and Cyanide Displacements via Hypervalent Silicate Intermediates
| العنوان: | ChemInform Abstract: Azide and Cyanide Displacements via Hypervalent Silicate Intermediates |
|---|---|
| المؤلفون: | Philip DeShong, Amy S. Manoso, Michael C. Patterson, Ralph Hirschmann, David A. Favor, Eric D. Soli, Amos B. Smith |
| المصدر: | ChemInform. 30 |
| بيانات النشر: | Wiley, 2010. |
| سنة النشر: | 2010 |
| مصطلحات موضوعية: | Substitution reaction, chemistry.chemical_classification, chemistry.chemical_compound, Nucleophile, Chemistry, Cyanide, Trimethylsilyl azide, Hypervalent molecule, General Medicine, Azide, Trimethylsilyl cyanide, Medicinal chemistry, Alkyl |
| الوصف: | Hypervalent azido- and cyanosilicate derivatives, prepared in situ by the reaction of trimethylsilyl azide or trimethylsilyl cyanide, respectively, with tetrabutylammonium fluoride, are effective sources of nucleophilic azide or cyanide. Primary and secondary alkyl halides and sulfonates undergo rapid and efficient azide or cyanide displacement in the absence of phase transfer catalysts with the silicate derivatives. Application of these reagents to the stereoselective synthesis of glycosyl azide derivatives is reported. |
| تدمد: | 1522-2667 0931-7597 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ef72261124860acd726e50a5ccc024cf https://doi.org/10.1002/chin.199937030 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........ef72261124860acd726e50a5ccc024cf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15222667 09317597 |
|---|