Stem Cell Transplantation for Multiple Myeloma: Single Center Experience

التفاصيل البيبلوغرافية
العنوان: Stem Cell Transplantation for Multiple Myeloma: Single Center Experience
المؤلفون: Nihan Alkis, Gurhan Kadikoylu, I. Yava oglu, Gokhan Pektas, Zahit Bolaman
المصدر: Clinical Lymphoma Myeloma and Leukemia. 15:e172
بيانات النشر: Elsevier BV, 2015.
سنة النشر: 2015
مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Mobilization, Neutrophil Engraftment, Platelet Engraftment, business.industry, Hematology, medicine.disease, Single Center, Gastroenterology, Transplantation, Platelet transfusion, Oncology, Internal medicine, medicine, Stem cell, business, Multiple myeloma
الوصف: e172 sessions. Thirteen (19.7%) patients were poor mobilizers. These patients had delay in neutrophil engraftment (p1⁄40.0004), platelet engraftment (p1⁄40.0002), had more platelet transfusion requirement (p1⁄40.03) and prolonged hospitalization (p1⁄40.02) compared to patients who were transplanted with stem cell dose of >3 10 cells/ kg. Univariate and step wise multiple regression was done to determine the factors predictive of poor mobilization (table 1). Receiver Operating Charecteristics (ROC) analysis to find out the cut-off of d4-PBCD34+ which was predictive of poor yield with 93% sensitivity and 77% specificity is 25/mL, with an AUROC of 0.89 (figure 1). Conclusion: Age >50 years, marrow involvement with disease prior to mobilization and a d4-PBCD34+ of 20/mL were significant predictors of poor mobilization in present study. A d4-PBCD34+ of
تدمد: 2152-2650
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f1983544b6f1da1a5efd8b7c237510d5
https://doi.org/10.1016/j.clml.2015.07.394
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........f1983544b6f1da1a5efd8b7c237510d5
قاعدة البيانات: OpenAIRE