Peri-interventional ischemic stroke after coronary angiography: a large-scale nationwide cohort analysis from 2006 to 2020
| العنوان: | Peri-interventional ischemic stroke after coronary angiography: a large-scale nationwide cohort analysis from 2006 to 2020 |
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| المؤلفون: | B Bay, A Gossling, M Remmel, L Koester, C M Blaum, P M Becher, E Zengin-Sahm, D L Rimmele, P Clemmensen, M Seiffert, S Blankenberg, F J Brunner, C Waldeyer |
| المصدر: | European Heart Journal. 43 |
| بيانات النشر: | Oxford University Press (OUP), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Cardiology and Cardiovascular Medicine |
| الوصف: | Background Ischemic stroke after coronary angiography is a life-threatening complication, leading to high mortality and long-term sequelae in surviving patients. Contemporary data from a European nationwide perspective are however lacking. Purpose We aimed to investigate the incidence, temporal trends, and outcome of ischemic stroke complicating coronary angiography in a German nationwide cohort. Methods A retrospective analysis of healthcare records from 2006–2020 based on ICD-10 and OPS codes obtained from the German Federal Statistical Office was carried out. Patients ≥18 years of age hospitalized for coronary angiography (both diagnostic and percutaneous interventions) were included in this analysis. Ischemic stroke events as well as co-morbidities were identified using ICD-10 and OPS codes. The outcome of interest was in-hospital mortality. Multivariable logistic regressions were computed for the association of ischemic stroke with in-hospital mortality adjusting for age, gender, hypertension, hyperlipoproteinemia, and diabetes mellitus. Results Overall 5,098,751 cases of patients undergoing coronary angiography (mean age 68.7±11.4 years; 28.0% female) between 2006 and 2020 were included. Ischemic stroke occurred in 3,808 (0.07%) patients. In comparison, individuals who suffered from peri-interventional ischemic stroke were older (70.8±11.1 vs. 68.7±11.4; p Conclusion In a contemporary nationwide cohort of patients hospitalized for coronary angiography spanning 15 years, the incidence of ischemic stroke remained low, although a gradual increase from 2006 to 2020 was documented. The occurrence of ischemic stroke was independently associated with a markedly increased risk of in-hospital mortality. These findings might be helpful in evaluating patients undergoing coronary angiography and to reduce the high mortality and morbidity associated with this complication in future. Funding Acknowledgement Type of funding sources: None. |
| تدمد: | 1522-9645 0195-668X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::f2c07ba092913155187a8e3fcb00bccc https://doi.org/10.1093/eurheartj/ehac544.2067 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi...........f2c07ba092913155187a8e3fcb00bccc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15229645 0195668X |
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