Using Secondary α Deuterium Kinetic Isotope Effects To Determine the Symmetry of SN2 Transition States
| العنوان: | Using Secondary α Deuterium Kinetic Isotope Effects To Determine the Symmetry of SN2 Transition States |
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| المؤلفون: | Yao-ren Fang, Kenneth Charles Westaway, and Thuy Van Pham |
| المصدر: | Journal of the American Chemical Society. 119:3670-3676 |
| بيانات النشر: | American Chemical Society (ACS), 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Chemistry, General Chemistry, Kinetic energy, Biochemistry, Catalysis, Transition state, Symmetry (physics), Colloid and Surface Chemistry, Deuterium, Atom, Kinetic isotope effect, SN2 reaction, Physical chemistry, Atomic physics |
| الوصف: | The secondary α deuterium and heavy atom kinetic isotope effects found for two different SN2 reactions suggest that the magnitude of secondary α deuterium kinetic isotope effects can be determined by the length of only the shorter (stronger) reacting bond in an unsymmetrical SN2 transition state rather than by the usual nucleophile−leaving group distance. Although this means the interpretation of these isotope effects is more complex than has been recognized, the results suggest that they can be used to determine whether an SN2 transition state is symmetrical or unsymmetrical. |
| تدمد: | 1520-5126 0002-7863 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::f300b50226f6ddfd7dd3405b719bb3cd https://doi.org/10.1021/ja962088f |
| رقم الأكسشن: | edsair.doi...........f300b50226f6ddfd7dd3405b719bb3cd |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15205126 00027863 |
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