Cleveland Clinic Cognitive Battery (C3B): Normative, Reliability, and Validation Studies of a Self-Administered Computerized Tool for Screening Cognitive Dysfunction in Primary Care
| العنوان: | Cleveland Clinic Cognitive Battery (C3B): Normative, Reliability, and Validation Studies of a Self-Administered Computerized Tool for Screening Cognitive Dysfunction in Primary Care |
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| المؤلفون: | Stephen M. Rao, Rachel Galioto, Megan Sokolowski, Madelyn Pierce, Lisa Penn, Anna Sturtevant, Blazenka Skugor, Brent Anstead, James B. Leverenz, David Schindler, David Blum, Jay L. Alberts, Lori Posk |
| المصدر: | Journal of Alzheimer's Disease. 92:1051-1066 |
| بيانات النشر: | IOS Press, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Psychiatry and Mental health, Clinical Psychology, General Neuroscience, General Medicine, Geriatrics and Gerontology |
| الوصف: | Background: The self-administered iPad-based Cleveland Clinic Cognitive Battery (C3B) was designed specifically for the efficient screening of cognitive functioning of older adults in a primary care setting. Objective: 1) Generate regression-based norms from healthy participants to enable demographic corrections to facilitate clinical interpretation; 2) estimate test-retest reliability and practice effects; 3) examine ability to discriminate mild cognitive impairment (MCI) from healthy aging; 4) d etermine validity of screening in a distracting clinical environment; and 5) determine completion rates and patient satisfaction in a primary care setting. Methods: Study 1 (S1) recruited a stratified sample of 428 healthy adults, ages 18–89, to generate regression-based equations. S2 assessed 2-week test-retest reliability and practice effects in 30 healthy elders. S3 recruited 30 MCI patients and 30 demographically-matched healthy controls. In S4, 30 healthy elders self-administered the C3B in a distracting environment and in a quiet private room in counterbalanced order. In a demonstration project, 470 consecutive primary care patients were administered the C3B as part of routine clinical care (S5). Results: C3B performance was primarily influenced by age, education, and race (S1), had acceptably high test-retest reliability and minimal practice effects (S2), discriminated MCI from healthy controls (S3), was not negatively impacted by a distracting clinical environment (S4), had high completion rates (>92%) and positive ratings from primary care patients (S5). Conclusion: The C3B is a computerized cognitive screening tool that is reliable, validated, self-administered, and is conducive to integration into a busy primary care clinical workflow for detecting MCI, early Alzheimer’s disease, and other related dementias. |
| تدمد: | 1875-8908 1387-2877 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::f4f712a3ff9f56259f58e623a99541cb https://doi.org/10.3233/jad-220929 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi...........f4f712a3ff9f56259f58e623a99541cb |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18758908 13872877 |
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