Prognostic value of platelet count in lung cancer: a systematic review and meta-analysis

التفاصيل البيبلوغرافية
العنوان: Prognostic value of platelet count in lung cancer: a systematic review and meta-analysis
المؤلفون: Qian Li, Wei Gu, Rong Su Fang, Yuan Yuan, Liang Ye, Hai Zhong, Ying Ying Qian
بيانات النشر: Research Square Platform LLC, 2019.
سنة النشر: 2019
مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.industry, Internal medicine, Meta-analysis, Medicine, Platelet, business, Lung cancer, medicine.disease, neoplasms, Value (mathematics)
الوصف: Background : The prognostic value of pretreatment elevated platelet count remains controversial in lung cancer patients. We performed the present meta-analysis to determine the precise role of it in these patients.Methods: We performed a multiple search strategy in PubMed database, EMBASE and Cochrane Library to identify eligible studies. Disease-free survival (DFS) /Progress-free survival (PFS)/Time to progress(TTP) and Overall survival (OS) were used as outcomes with hazard ratio (HR) and its 95% confidence intervals (CIs). Heterogeneity among studies and publication bias were also evaluated.Results : A total of 39 studies including 16696 lung cancer patients were eligible in the analysis. Overall, the pooled analysis showed that pretreatment elevated platelet count was associated with poorer OS (HR= 1.47, 95%CI: 1.31-1.66, P
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f8ef891cfa4d3a73c4f0dec9c5194a10
https://doi.org/10.21203/rs.2.16573/v1
حقوق: OPEN
رقم الأكسشن: edsair.doi...........f8ef891cfa4d3a73c4f0dec9c5194a10
قاعدة البيانات: OpenAIRE