Two Cu(II)-based coordination polymers: reduction activity on serum procalcitonin production and protective effect on children sepsis
| العنوان: | Two Cu(II)-based coordination polymers: reduction activity on serum procalcitonin production and protective effect on children sepsis |
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| المؤلفون: | Y.-Q. Liu, F.-Z. Liu, Y.-J. Liu, J. Zhang, Q.-X. Xiong |
| المصدر: | Журнал структурной химии. 61:2114-2121 |
| بيانات النشر: | NIIC SB RAS, 2020. |
| سنة النشر: | 2020 |
| الوصف: | In the current study, by applying the mixed-ligand approach, two new Cu(II)-based coordination polymers with the chemical formulae of {[Cu(Py2TTz)(BDC)](DMF)}n (1) and {[Cu2(Py2TTz)2(BDC)2]·2(DMF)·0.5(H2O)}n (2) are successfully prepared from a rigid N-donor linker 2,5-bis(4-pyridyl)thiazolo[5,4-d]thiazole (Py2TTz) and linear carboxylate ligands of 1,4-benzenedicarboxylic acid (H2BDC) under different reaction conditions. Then, the therapeutic activity of the compounds on the children sepsis is evaluated. Firstly, the percentage of lymphocyte apoptosis after treating with the compounds is measured with the V-FITC/PI staining assay. Next, the serum procalcitonin (PCT) content during sepsis after treating with the compounds is determined with the ELISA detection kit. |
| تدمد: | 2542-0976 0136-7463 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::fd4330afbd81c62d73aee40010e8a195 https://doi.org/10.26902/jsc_id65985 |
| رقم الأكسشن: | edsair.doi...........fd4330afbd81c62d73aee40010e8a195 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 25420976 01367463 |
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