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Oxidative stress induced by MPTP and MPP+: selective vulnerability of cultured mouse astrocytes1Published on the World Wide Web on 18 June 1999.1

التفاصيل البيبلوغرافية
العنوان: Oxidative stress induced by MPTP and MPP+: selective vulnerability of cultured mouse astrocytes1Published on the World Wide Web on 18 June 1999.1
المؤلفون: Raymond H.Y. Li, Steve S Wong, Alfreda Stadlin
المصدر: Brain Research. 836:237-244
بيانات النشر: Elsevier BV, 1999.
سنة النشر: 1999
مصطلحات موضوعية: chemistry.chemical_classification, medicine.medical_specialty, Reactive oxygen species, General Neuroscience, MPTP, 1-Methyl-4-phenylpyridinium, Biology, medicine.disease_cause, Superoxide dismutase, chemistry.chemical_compound, medicine.anatomical_structure, Endocrinology, nervous system, chemistry, Internal medicine, medicine, biology.protein, Neurotoxin, Neuroglia, Neurology (clinical), Molecular Biology, Neuroscience, Oxidative stress, Developmental Biology, Astrocyte
الوصف: Oxidative stress has been implicated in the pathogenesis of Parkinson's disease. In the present study, reactive oxygen species (ROS) formation and antioxidant enzyme superoxide dismutase (SOD) activities were examined in cultured cortical, striatal and mesencephalic mouse astrocytes after 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) or 1-methyl-4-phenylpyridinium (MPP(+)) treatment. Linear regression analysis showed that control mesencephalic (slope coefficient=0.01) astrocytes had a three-fold (F-test, p
تدمد: 0006-8993
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd4e71222eda166c81b785c454a9b5df
https://doi.org/10.1016/s0006-8993(99)01661-3
حقوق: CLOSED
رقم الأكسشن: edsair.doi...........fd4e71222eda166c81b785c454a9b5df
قاعدة البيانات: OpenAIRE
الوصف
تدمد:00068993