Electrochemical Detection of the Exhaled Nitric Oxide in Children
| العنوان: | Electrochemical Detection of the Exhaled Nitric Oxide in Children |
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| المؤلفون: | Sorin Berbece, Florentina Dumitrescu, radu Diaconu, Loredana Nicoleta Stoica, Loredana Selaru, Iustina Violeta Stan, Ion Udristoiu, Ovidiu Ciobanu |
| المصدر: | Revista de Chimie. 71:105-109 |
| بيانات النشر: | Revista de Chimie SRL, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Process equipment, Chemistry, Materials Science (miscellaneous), Process Chemistry and Technology, Inorganic chemistry, General Engineering, General Chemistry, General Medicine, Electrochemical detection, General Biochemistry, Genetics and Molecular Biology, Petrochemistry, Exhaled nitric oxide, Materials Chemistry, General Pharmacology, Toxicology and Pharmaceutics |
| الوصف: | Dosage of gaseous inflammatory markers is a promising method of evaluating various types of pediatric pathologies and not only. The fraction of exhaled nitric oxide (FeNO) can be quantified by electrochemical detection using a portable analyzer that delivers fast, reproducible, and widely available results. The objectives of our study were to evaluate the accessibility of the pediatric dosing method and the utility of FeNO for the diagnosis of atopic pathology in hospitalized children. We conducted a retrospective study that included children aged over 6 years admitted to the Pediatric Department of the Municipal Hospital Filantropia in Craiova who were evaluated according to the type of training performed for the determination of FeNO and according to the diagnosis of admission. Results. Using a human model was more effective in obtaining a valid result compared to the use of the demo provided by the manufacturer, especially at younger age (p = 0.05 and respectively, 0.04 - Student t test). Among the various allergic pathologies studied, children with asthma were the ones who recorded the highest levels of nitric oxide, even when compared to the rest of atopic children (p = 0.01 - t test). Moreover, the proportion of cases with positive values was increased in asthmatic children compared to the rest of the type of allergic pathology, but these values were at the limit of statistical significance (p = 0.08 - chi square and Mid-P exact test). The conclusion of our study was that it is possible to improve compliance with FeNO assessment especially at younger age, and the utility of the method is still limited, especially in asthma cases. |
| تدمد: | 2668-8212 0034-7752 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_________::ff249089b1102015bba4faed404ed478 https://doi.org/10.37358/rc.20.2.7900 |
| رقم الأكسشن: | edsair.doi...........ff249089b1102015bba4faed404ed478 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26688212 00347752 |
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