Serotonin 1A receptors and sexual behavior in female rats: a review

التفاصيل البيبلوغرافية
العنوان: Serotonin 1A receptors and sexual behavior in female rats: a review
المؤلفون: Berend Olivier, Jan G. Veening, Eelke M.S. Snoeren, Ronald S. Oosting
المصدر: Pharmacology, Biochemistry and Behavior, 121, 43-52
Pharmacology, Biochemistry and Behavior, 121, pp. 43-52
سنة النشر: 2014
مصطلحات موضوعية: Male, medicine.medical_specialty, Serotonin, Clinical Biochemistry, Posture, Other Research Donders Center for Medical Neuroscience [Radboudumc 0], Toxicology, Biochemistry, Behavioral Neuroscience, Sexual Behavior, Animal, Internal medicine, Male rats, Copulation, medicine, Animals, Biogenic Monoamines, Receptor, Biological Psychiatry, 5-HT receptor, Pharmacology, Sex Characteristics, Brain, Rats, Endocrinology, Sexual behavior, Receptor, Serotonin, 5-HT1A, Female, Psychology
الوصف: Contains fulltext : 133884.pdf (Publisher’s version ) (Closed access) This review focuses on the role of serotonin and especially 5-HT(1)A receptors in female rat sexual behavior. In addition, the differences and/or similarities with male rats are discussed. Overall, in both males and females 5-HT(1)A receptors do not appear to be involved in sexual behavior under normal circumstances, but become very important under conditions of elevated serotonin levels. 5-HT(1)A receptor agonists facilitate sexual behavior in male rats, but inhibit female sexual activity. At first sight, this seems quite conflicting, but could be due to our definitions of different elements of sexual behavior. Three different phases can be distinguished in rats' sexual cycle, the introductory (precopulatory), the copulatory and the executive (ejaculatory) phases. Different mechanisms and brain regions are involved in these phases. If the appropriate phases of males and females are properly compared, the role of 5-HT(1)A receptors in rats might be more similar than assumed thus far. 01 juni 2014
وصف الملف: application/pdf
تدمد: 0091-3057
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::005b1414fb85265ac28983490d0a3364
https://doi.org/10.1016/j.pbb.2013.11.017
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....005b1414fb85265ac28983490d0a3364
قاعدة البيانات: OpenAIRE