Gastric Emptying in Trauma Patients
| العنوان: | Gastric Emptying in Trauma Patients |
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| المؤلفون: | C.L. Long, J.W. Geiger, L. Borghesi, D.A. Wagner, P.H. Scanlon, C.B. Carlin |
| المصدر: | Digestive Surgery. 16:192-196 |
| بيانات النشر: | S. Karger AG, 1999. |
| سنة النشر: | 1999 |
| مصطلحات موضوعية: | Adult, Male, Carbon Isotopes, medicine.medical_specialty, Trauma Severity Indices, Gastric emptying, business.industry, Phenylalanine, digestive, oral, and skin physiology, Gastroenterology, Trauma care, digestive system diseases, Enteral Nutrition, Gastric Emptying, Intestinal Absorption, Case-Control Studies, medicine, Humans, Wounds and Injuries, Female, Surgery, Intensive care medicine, business |
| الوصف: | Background/Aim: The aim of this study was to obtain quantitative data on gastric emptying following trauma. Methods: In order to assess gastric emptying for early enteral feeding, we evaluated the absorption of an amino acid, L-[1-13C]phenylalanine, within 24 h of admission and 7 days later in 14 trauma patients (injury severity score 36 ± 2). Following nasogastric administration of 100 mg L-[1-13C]phenylalanine, the plasma L-[1-13C]phenylalanine enrichment at 30 and 60 min and the expired 13CO2 for 1 h in the breath were used to measure the degree of gastric emptying. Results: The plasma L-[1-13C]phenylalanine enrichment concentration at 30 min was 0.53 ± 0.23 mmol/l during the first study and 2.46 ± 0.62 mmol/l during the second study (p = 0.006, a fivefold increase). The L-[1-13C]phenylalanine plasma level in historic controls was 4.57 ± 1.48 mmol/l. The percent of the dose oxidized and expired as 13CO2 in 1 h was 0.51 ± 0.17 during the first 24-hour study compared to the second study of 3.37 ± 0.68 (p = 0.0008) 7 days later (an over sixfold increase). The percent of the dose oxidized in 1 h in 37 normal historic controls was 7.08 ± 0.33. Conclusion: These data indicate delayed gastric emptying with limited recovery in 1 week. We conclude that gastric feeding should not be employed, and the route for early nutritional intervention should be transpyloric for the trauma patient. |
| تدمد: | 1421-9883 0253-4886 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ceb1f85525234447b5a09571051d5e https://doi.org/10.1159/000018726 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....00ceb1f85525234447b5a09571051d5e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14219883 02534886 |
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