A Noninvasive Miniaturized Transcutaneous Oxygen Monitor
| العنوان: | A Noninvasive Miniaturized Transcutaneous Oxygen Monitor |
|---|---|
| المؤلفون: | Ian Costanzo, Devdip Sen, Joseph Olanrewaju Adegite, Ulkuhan Guler, Pratap M. Rao |
| المصدر: | IEEE Transactions on Biomedical Circuits and Systems. 15:474-485 |
| بيانات النشر: | Institute of Electrical and Electronics Engineers (IEEE), 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Materials science, Partial Pressure, System of measurement, Biomedical Engineering, Arterial oxygen, chemistry.chemical_element, Partial pressure, Carbon Dioxide, Temperature measurement, Oxygen, Intensity (physics), law.invention, Pressure measurement, chemistry, law, Humans, Electrical and Electronic Engineering, Transcutaneous oxygen, Monitoring, Physiologic, Skin, Biomedical engineering |
| الوصف: | Transcutaneous monitoring is a noninvasive method to continuously measure the partial pressures of oxygen and carbon dioxide that diffuse through the skin and correlate closely with changes in blood gases. However, the contemporary commercially available electrochemical-based technology requires a heating mechanism and a bulky, corded, and expensive sensing unit. This study aims to demonstrate a prototype noninvasive, miniaturized monitor that uses luminescence-based technology to measure the partial pressure of transcutaneous oxygen, a surrogate of the partial pressure of arterial oxygen. To be able to build a robust measurement system, we conducted experiments to understand the temperature and humidity dependence of oxygen-sensitive platinum-porphyrin films. We performed a detailed analysis of both intensity and lifetime measurement techniques. To verify the performance, we tested the prototype in a small ex-vivo experiment involving three healthy human volunteers. We measured variations in the partial pressure of transcutaneous oxygen values due to pressure-induced arterial and venous occlusions on the volunteers' fingertips. The system resolves changes in the partial pressure of oxygen from 0 to 418 mmHg in the lab bench-top testing, covering the medically relevant range of 50-150 mmHg. Under fixed humidity, temperature, and the partial pressure of oxygen conditions, the sensor shows a 2% drift over 60 hours. The prototype consumes 9 mW of power from a 2.2 V external DC power supply. |
| تدمد: | 1940-9990 1932-4545 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a8a17471ce2f53a77604310d194601 https://doi.org/10.1109/tbcas.2021.3094931 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....01a8a17471ce2f53a77604310d194601 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19409990 19324545 |
|---|