Nutritional and Pharmacological Effects on Oxidative Stress in Soft Tissue and Bone Remodeling
| العنوان: | Nutritional and Pharmacological Effects on Oxidative Stress in Soft Tissue and Bone Remodeling |
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| المؤلفون: | Naren Patel, Benjamin M. Savasky, Edgardo Rodriguez-Collazo, David P. Mascotti |
| المصدر: | Journal of Nutrition and Metabolism, Vol 2018 (2018) Journal of Nutrition and Metabolism |
| بيانات النشر: | Hindawi Limited, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Heart disease, Endocrinology, Diabetes and Metabolism, Arthritis, 030209 endocrinology & metabolism, Inflammation, Disease, Review Article, Bioinformatics, medicine.disease_cause, Bone remodeling, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Medicine, lcsh:RC620-627, Asthma, Nutrition and Dietetics, business.industry, medicine.disease, lcsh:Nutritional diseases. Deficiency diseases, 030104 developmental biology, medicine.symptom, business, Oxidative stress, Food Science |
| الوصف: | Oxidative damage is the causal link to a multitude of pathologies, such as diabetes, arthritis, neuropathy, heart disease, and asthma. These conditions affect hundreds of millions of people nationwide, and billions worldwide. Even in otherwise healthy individuals, oxidative stress is a natural byproduct of metabolism that is augmented in “healthy” activities such as athletics. In many disease states, the pharmacological agents used to treat these conditions can induce oxidative damage and vitamin depletion. It is underappreciated by many that many of the most common medications prescribed result in oxidative stress. Therefore, physicians need to carefully scrutinize which medications their patients are on before surgery and treatment and during the recovery stage to obtain optimal healing results. We provide a review of the current literature of how oxidative damage and inflammation are linked to bone damage, Charcot neuroarthropathy, delayed wound healing, diabetic complications, and delayed flap consolidation. Where available, antioxidant intervention literature is offered to offset these conditions. |
| اللغة: | English |
| تدمد: | 2090-0732 2090-0724 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0258d5a384ef035a2fc4d9dd2f19eda7 https://doaj.org/article/c4e87a9e2c8c4d7c837c5bb8a31fa114 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0258d5a384ef035a2fc4d9dd2f19eda7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20900732 20900724 |
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