The analysis of 2′-fucosyllactose concentration in Korean maternal milk using LC–MS/MS

التفاصيل البيبلوغرافية
العنوان: The analysis of 2′-fucosyllactose concentration in Korean maternal milk using LC–MS/MS
المؤلفون: My Tuyen T. Nguyen, Nari Seo, Yong-Ki Kim, Ji A. Jung, Hyun Joo An, Jung-Min Kim, Young-Ha Song, Jaehan Kim, Jong-Won Yoon
المصدر: Food Science and Biotechnology. 31:1661-1666
بيانات النشر: Springer Science and Business Media LLC, 2022.
سنة النشر: 2022
مصطلحات موضوعية: Applied Microbiology and Biotechnology, Food Science, Biotechnology
الوصف: Despite health benefits reported recently, 2'-fucosyllactose (2'-FL) concentration in maternal milk was not conclusively reported because it varies between countries and mothers. Particularly, its distribution among Korean mothers was not obtained from a reliable sample group yet. Thus, a dynamic range for 2'-FL concentration in Korean mothers' milk was investigated from 102 samples. A quantitative method using multiple reaction monitoring (MRM) by triple-quadrupole-mass spectrometry has been evaluated by a standard procedure of method validation. The 2'-FL concentration was in the range of 0.4 to 2.6 g/L overall. While the samples from secretor mothers (n = 80) contained 1.0 to 2.8 g/L of 2'-FL, the maternal milk from non-secretor mothers (n = 22) had 0.01 to 0.06 g/L of 2'-FL only. In addition to the genetic variation of mothers, the lactation period impacted the 2'-FL concentration. The average 2'-FL concentration of the late-stage group ( 60 days) was 78% of that obtained from the first month of postpartum mothers.The online version contains supplementary material available at 10.1007/s10068-022-01154-4.
تدمد: 2092-6456
1226-7708
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0259fd9fdc55bf6e7928e18d500088f6
https://doi.org/10.1007/s10068-022-01154-4
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....0259fd9fdc55bf6e7928e18d500088f6
قاعدة البيانات: OpenAIRE