Amplatzer Vascular Plugs Versus Coils for Embolization of Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia
| العنوان: | Amplatzer Vascular Plugs Versus Coils for Embolization of Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia |
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| المؤلفون: | Gil N. Bachar, Noam Tau, E. Atar, Tamir Dagan, Einat Birk, Elchanan Bruckheimer, Meir Mei-Zahav |
| المصدر: | CardioVascular and Interventional Radiology. 39:1110-1114 |
| بيانات النشر: | Springer Science and Business Media LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Computed Tomography Angiography, medicine.medical_treatment, Pulmonary Artery, 030204 cardiovascular system & hematology, 030218 nuclear medicine & medical imaging, Osler weber rendu, Arteriovenous Malformations, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Blood vessel prosthesis, medicine.artery, medicine, Humans, Radiology, Nuclear Medicine and imaging, In patient, Embolization, Child, Telangiectasia, Aged, Retrospective Studies, Computed tomography angiography, Coil embolization, medicine.diagnostic_test, business.industry, Middle Aged, Embolization, Therapeutic, Blood Vessel Prosthesis, Surgery, Treatment Outcome, Pulmonary Veins, Pulmonary artery, Female, Telangiectasia, Hereditary Hemorrhagic, Radiology, medicine.symptom, Cardiology and Cardiovascular Medicine, business |
| الوصف: | Coil embolization of pulmonary arteriovenous malformations (PAVMs) has a high re-canalization/re-perfusion rate. Embolization with Amplatzer plugs has been previously described, but the long-term efficacy is not established. This study reports the experience of a referral medical center with the use of coils and Amplatzer plugs for treating PAVMs in patients with hereditary hemorrhagic telangiectasia.The study was approved by the Institutional Review Board with waiver of informed consent. The cohort included all patients who underwent PAVM embolization in 2004-2014 for whom follow-up imaging scans were available. The medical files were retrospectively reviewed for background data, embolization method (coils, Amplatzer plugs, both), and complications. Re-canalization of treated PAVMs was assessed from intrapulmonary angiograms (following percutaneous procedures) or computed tomography angiograms. Fisher's exact test and Pearson Chi-squared test or t test were used for statistical analysis, with significance at p 0.05.16 patients met the study criteria. Imaging scans were available for 63 of the total 110 PAVMs treated in 41 procedures. Coils were used for embolization in 37 PAVMs, Amplatzer plugs in 21, and both in five. Median follow-up time was 7.7 years (range 1.4-18.9). Re-canalization was detected in seven vessels, all treated with coils; there were no cases of re-canalization in plug-occluded vessels (p = 0.0413).The use of Amplatzer plugs for the embolization of PAVMs in patients with hemorrhagic telangiectasia is associated with a significantly lower rate of re-canalization of feeding vessels than coils. Long-term prospective studies are required to confirm these findings. |
| تدمد: | 1432-086X 0174-1551 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0427206c10b3c7791a0734eb76f6b516 https://doi.org/10.1007/s00270-016-1357-7 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....0427206c10b3c7791a0734eb76f6b516 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 1432086X 01741551 |
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