Propagation of Dengue Viruses in Murine Cell Cultures *
| العنوان: | Propagation of Dengue Viruses in Murine Cell Cultures * |
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| المؤلفون: | Joe L. Elm, Wayne C. Koff, Scott B. Halstead |
| المصدر: | The American Journal of Tropical Medicine and Hygiene. 30:461-464 |
| بيانات النشر: | American Society of Tropical Medicine and Hygiene, 1981. |
| سنة النشر: | 1981 |
| مصطلحات موضوعية: | Mice, Inbred BALB C, Virus Cultivation, viruses, Dengue Virus, Biology, Dengue virus, medicine.disease, medicine.disease_cause, Virology, Virus, Dengue fever, Mice, Titer, Infectious Diseases, Immune system, Viral replication, medicine, Animals, Parasitology, Antibody-dependent enhancement, Murine cell |
| الوصف: | Dengue viruses were cultivated in Balb 3T12-3 cells, a continuous line of cells derived from mouse embryo cell cultures. Optimal serum concentrations were determined for maximal kinetics of virus replication. All four types of dengue viruses replicate in these cells, and peak virus titers were obtained by 72 hours post-infection. The successful growth of dengue viruses in a continuous line of mouse cells should allow for more extensive studies examining the cellular immune response to dengue virus infection in murine models. |
| تدمد: | 1476-1645 0002-9637 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04950a566e35d482cb5e09622e547bcf https://doi.org/10.4269/ajtmh.1981.30.461 |
| رقم الأكسشن: | edsair.doi.dedup.....04950a566e35d482cb5e09622e547bcf |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14761645 00029637 |
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