Interferon Gamma-Induced Protein (IP-10) as Potential Biomarker for Cancer-Related-Fatigue: Results from a 6-month Randomized Controlled Trial
| العنوان: | Interferon Gamma-Induced Protein (IP-10) as Potential Biomarker for Cancer-Related-Fatigue: Results from a 6-month Randomized Controlled Trial |
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| المؤلفون: | Tineke C. T. M. van der Pouw Kraan, Eddy A. Wierenga, Gijs Bleijenberg, I. Jolanda M. de Vries, Hetty Prinsen, Hanneke W. M. van Laarhoven, Mirjam A. G. Sprangers, Emil ter Veer, Koos H. Zwinderman |
| المساهمون: | Graduate School, AGEM - Re-generation and cancer of the digestive system, APH - Quality of Care, CCA - Imaging and biomarkers, APH - Methodology, Medical Psychology, APH - Mental Health, APH - Personalized Medicine, Epidemiology and Data Science, Experimental Immunology, Oncology, APH - Aging & Later Life, ACS - Atherosclerosis & ischemic syndromes, Molecular cell biology and Immunology, AGEM - Digestive immunity, VU University medical center |
| المصدر: | Cancer Investigation, 36, 7, pp. 371-377 Cancer investigation, 36(7), 371-377. Informa Healthcare ter Veer, E, Prinsen, H, Sprangers, M A G, Zwinderman, K A H, Bleijenberg, G, van der Pouw Kraan, T C T M, de Vries, I J M, Wierenga, E A & van Laarhoven, H W M 2018, ' Interferon Gamma-Induced Protein (IP-10) as Potential Biomarker for Cancer-Related-Fatigue: Results from a 6-month Randomized Controlled Trial ', Cancer Investigation, vol. 36, no. 7, pp. 371-377 . https://doi.org/10.1080/07357907.2018.1499933 Cancer Investigation, 36(7), 371-377. Informa Healthcare Cancer Investigation, 36, 371-377 |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, Adult, Male, Cancer Research, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Cancer development and immune defence Radboud Institute for Molecular Life Sciences [Radboudumc 2], Gastroenterology, Severity of Illness Index, law.invention, 03 medical and health sciences, Cancer development and immune defence Radboud Institute for Health Sciences [Radboudumc 2], 0302 clinical medicine, All institutes and research themes of the Radboud University Medical Center, Randomized controlled trial, Interferon, law, Predictive Value of Tests, Internal medicine, Neoplasms, medicine, Humans, Interferon gamma, Longitudinal Studies, Cancer-related fatigue, Fatigue, Cognitive Behavioral Therapy, business.industry, Cancer, General Medicine, Middle Aged, medicine.disease, Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], Cognitive behavioral therapy, Chemokine CXCL10, 030104 developmental biology, Cross-Sectional Studies, Treatment Outcome, Oncology, 030220 oncology & carcinogenesis, Potential biomarkers, Biomarker (medicine), Female, medicine.symptom, business, Biomarkers, medicine.drug |
| الوصف: | We examined if serum concentrations Interferon gamma-induced protein (IP-10) is a potential clinical biomarker for cancer-related-fatigue (CRF). Fatigue scores and IP-10 concentrations were measured from curatively treated fatigued cancer patients randomized to either cognitive behavioral therapy (CBT, n = 26) or waiting-list (WL, n = 13). No correlation was found between baseline IP-10 level and fatigue severity and no significant differences in IP-10 serum levels were observed between fatigued and matched non-fatigued patients (n = 22). Relative changes in IP-10 concentrations from baseline to six-month follow-up were not significantly different between the CBT and WL conditions. In this study, IP-10 showed low potential as clinical CRF biomarker. Trial registration: This study is registered at ClinicalTrials.gov (NCT01096641). |
| وصف الملف: | application/pdf |
| تدمد: | 0735-7907 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051f85a20dcfd353dfb1209938235de4 https://hdl.handle.net/2066/196911 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....051f85a20dcfd353dfb1209938235de4 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 07357907 |
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