Situation of multidrug-resistant pulmonary tuberculosis in Alexandria governorate from July 2008 to December 2012
| العنوان: | Situation of multidrug-resistant pulmonary tuberculosis in Alexandria governorate from July 2008 to December 2012 |
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| المؤلفون: | Mostafa E. Zaki, Osama I. Mohammad, Ali A. Okab |
| المصدر: | The Egyptian Journal of Bronchology, Vol 10, Iss 1, Pp 64-68 (2016) |
| بيانات النشر: | Springer Science and Business Media LLC, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | 0301 basic medicine, Pediatrics, medicine.medical_specialty, Tuberculosis, pulmonary, Prevalence, 03 medical and health sciences, 0302 clinical medicine, Pulmonary tuberculosis, medicine, 030212 general & internal medicine, Ethambutol, lcsh:RC705-779, business.industry, multidrug resistant, lcsh:Medical emergencies. Critical care. Intensive care. First aid, Retrospective cohort study, lcsh:Diseases of the respiratory system, lcsh:RC86-88.9, medicine.disease, Multiple drug resistance, 030104 developmental biology, tuberculosis, Streptomycin, business, Rifampicin, medicine.drug |
| الوصف: | Aim The aim of this study was to estimate the prevalence, possible risk factors, patterns of resistance, and fate of multidrug-resistant pulmonary tuberculosis (MDR-TB) in Alexandria governorate as a representative part of Egypt during the period between July 2008 and December 2012. Patients and methods This retrospective study included all patients with pulmonary TB that was recorded in Alexandria governorate during the period between July 2008 (the time that MDR ward was held in Alexandria) and December 2012. They were divided into two groups: group I included patients with pulmonary TB that was recorded in Alexandria governorate (1893 cases), and group II included patients with pulmonary TB who were admitted in El-Maamoura Chest Hospital (509 cases). They were subdivided into two subgroups: group IIa included patients with MDR pulmonary TB (82 cases), and group IIb included patients with pulmonary TB not categorized as MDR-TB (427 cases). Results All patients with MDR-TB had acquired resistance. MDR-TB was more common in the male population, diabetic patients, and those with chronic chest disease. The effect of treatment of MDR-TB cases was as follows: cured patients, 49 (59.8%); patients under treatment, 10 (12.2%); treatment failure, four cases (4.9%); deceased patients, 10 (12.2%); and defaulters, nine (10.9%). The overall total prevalence rate of MDR-TB in Alexandria governorate from 2008 to 2012 was 4.3%. Conclusion There was a decreasing trend of MDR-TB cases. History of anti-TB treatment is the strongest independent predictor of MDR-TB. The highest figures of resistance in the MDR group besides isoniazide and rifampicin were for streptomycin, whereas the lowest resistance was for ethambutol. |
| تدمد: | 2314-8551 1687-8426 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0621500ee71e5e8e77a4150d4be7bed6 https://doi.org/10.4103/1687-8426.176792 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0621500ee71e5e8e77a4150d4be7bed6 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 23148551 16878426 |
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