Thermoresponsive Liposomes for Photo-Triggered Release of Hypericin Cyclodextrin Inclusion Complex for Efficient Antimicrobial Photodynamic Therapy

التفاصيل البيبلوغرافية
العنوان: Thermoresponsive Liposomes for Photo-Triggered Release of Hypericin Cyclodextrin Inclusion Complex for Efficient Antimicrobial Photodynamic Therapy
المؤلفون: Alice Abu Dayyih, Bernd Gutberlet, Eduard Preis, Konrad H. Engelhardt, Muhammad Umair Amin, Ahmed M. Abdelsalam, Martina Bonsu, Udo Bakowsky
المصدر: ACS applied materialsinterfaces. 14(28)
سنة النشر: 2023
مصطلحات موضوعية: Anthracenes, Cyclodextrins, Mice, Photochemotherapy, Liposomes, Animals, General Materials Science, Fibroblasts, Perylene, Anti-Bacterial Agents
الوصف: Antimicrobial strategies with high efficacy against bacterial infections are urgently needed. The development of effective therapies to control bacterial infections is still a challenge. Herein, near-infrared (NIR)-activated thermosensitive liposomes (TSL) were loaded with the NIR-dye 1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide (DiR) and the water-soluble hypericin (Hyp) β-cyclodextrin inclusion complex (Hyp-βCD). DiR and Hyp-βCD loaded thermosensitive liposomes (DHβCD-TSL) are functionalized for photothermal triggered release and synergistic photodynamic therapy to eliminate the gram-positive
تدمد: 1944-8252
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a66a9d9eab5e96a180ab7c0c660e34
https://pubmed.ncbi.nlm.nih.gov/35790214
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....06a66a9d9eab5e96a180ab7c0c660e34
قاعدة البيانات: OpenAIRE