Outcome of patients admitted with acute coronary syndrome on palliative treatment: insights from the nationwide AMIS Plus Registry 1997-2014
| العنوان: | Outcome of patients admitted with acute coronary syndrome on palliative treatment: insights from the nationwide AMIS Plus Registry 1997-2014 |
|---|---|
| المؤلفون: | Paul, Erne, Dragana, Radovanovic, Burkhardt, Seifert, Osmund, Bertel, Philip, Urban, S, Christen |
| المساهمون: | University of Zurich, Erne, Paul, AMIS Plus Investigators, Lessing, P., Hess, F., Simon, R., Hangartner, PJ., Hufschmid, U., Hornig, B., Jeger, R., Trummler, S., Windecker, S., Rueff, T., Loretan, P., Roethlisberger, C., Evéquoz, D., Mang, G., Ryser, D., Müller, P., Jecker, R., Kistler, W., Droll, A., Stäuble, S., Freiwald, G., Schmid, HP., Stauffer, JC., Cook, S., Bietenhard, K., Roffi, M., Wojtyna, W., Schönenberger, R., Simonin, C., Waldburger, R., Schmidli, M., Federspiel, B., Weiss, EM., Marty, H., Weber, K., Zender, H., Poepping, I., Hugi, A., Koltai, E., Iglesias, JF., Pedrazzini, G., Erne, P., Cuculi, F., Heimes, T., Jordan, B., Pagnamenta, A., Urban, P., Feraud, P., Beretta, E., Stettler, C., Repond, F., Widmer, F., Heimgartner, C., Polikar, R., Bassetti, S., Iselin, HU., Giger, M., Egger, P., Kaeslin, T., Fischer, A., Herren, T., Eichhorn, P., Neumeier, C., Flury, G., Girod, G., Vogel, R., Niggli, B., Rickli, H., Nossen, J., Stoller, U., Veragut, UP., Bächli, E., Weber, A., Schmidt, D., Hellermann, J., Eriksson, U., Fischer, T., Peter, M., Gasser, S., Fatio, R., Vogt, M., Ramsay, D., Bertel, O., Maggiorini, M., Eberli, F., Christen, S. |
| المصدر: | Bmj Open, vol. 5, no. 3, pp. e006218 BMJ Open |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Acute coronary syndrome, Palliative care, medicine.medical_treatment, Myocardial Infarction, Shock, Cardiogenic, 610 Medicine & health, Platelet Glycoprotein GPIIb-IIIa Complex, 2700 General Medicine, Cardiovascular Medicine, 11171 Cardiocentro Ticino, Cohort Studies, Reperfusion therapy, Internal medicine, Prevalence, medicine, Humans, Thrombolytic Therapy, Hospital Mortality, Registries, Myocardial infarction, Acute Coronary Syndrome, Angioplasty, Balloon, Coronary, Intensive care medicine, Prospective cohort study, Aged, Aged, 80 and over, Heart Failure, Heparin, business.industry, Research, Palliative Care, Age Factors, Anticoagulants, Percutaneous coronary intervention, General Medicine, Thrombolysis, 10060 Epidemiology, Biostatistics and Prevention Institute (EBPI), Middle Aged, medicine.disease, Treatment Outcome, Purinergic P2Y Receptor Antagonists, Female, business, Switzerland, Cohort study |
| الوصف: | OBJECTIVE: Compliance with guidelines is increasingly used to benchmark the quality of hospital care, however, very little is known on patients admitted with acute coronary syndromes (ACS) and treated palliatively. This study aimed to evaluate the baseline characteristics and outcomes of these patients. DESIGN: Prospective cohort study. SETTING: Eighty-two Swiss hospitals enrolled patients from 1997 to 2014. PARTICIPANTS: All patients with ACS enrolled in the AMIS Plus registry (n=45,091) were analysed according to three treatment groups: palliative treatment, defined as use of aspirin and analgesics only and no reperfusion; conservative treatment, defined as any treatment including antithrombotics or anticoagulants, heparins, P2Y12 inhibitors, GPIIb/IIIa but no pharmacological or mechanical reperfusion; and reperfusion treatment (thrombolysis and/or percutaneous coronary intervention during initial hospitalisation). The primary outcome measure was in-hospital mortality and the secondary measure was 1-year mortality. RESULTS: Of the patients, 1485 (3.3%) were palliatively treated, 11,119 (24.7%) were conservatively treated and 32,487 (72.0%) underwent reperfusion therapy. In 1997, 6% of all patients were treated palliatively and this continuously decreased to 2% in 2013. Baseline characteristics of palliative patients differed in comparison with conservatively treated and reperfusion patients in age, gender and comorbidities (all p |
| وصف الملف: | BMJ Open-2015-Erne-.pdf - application/pdf; application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0706a2741badf6cbcea497dae4bb03a0 https://doi.org/10.5167/uzh-110007 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0706a2741badf6cbcea497dae4bb03a0 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |