Novel Antihyperglycemic Terpenoid-Quinones from Pycnanthus angolensis
| العنوان: | Novel Antihyperglycemic Terpenoid-Quinones from Pycnanthus angolensis |
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| المؤلفون: | Chen Jl, Shivanand D. Jolad, Donald Bierer, Ianiro Tt, Reimar C. Bruening, J. Luo, Carney, King, C. D. Mendez, Rosa P. Ubillas, Wayne D. Inman, T. J. Carlson, Raymond Cooper, Hasbun C, Iwu M, M. J. Reed, Diana M. Fort |
| المصدر: | The Journal of Organic Chemistry. 65:6534-6539 |
| بيانات النشر: | American Chemical Society (ACS), 2000. |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | Blood Glucose, Male, Magnetic Resonance Spectroscopy, Pycnanthus angolensis, Mice, Obese, Myristicaceae, Eating, Mice, Diabetes Mellitus, Animals, Hypoglycemic Agents, Plants, Medicinal, Plant Stems, biology, Traditional medicine, Plant Extracts, Chemistry, Body Weight, Organic Chemistry, Diabetic mouse, biology.organism_classification, Terpenoid, Quinone, Mice, Inbred C57BL, Plant Leaves, Africa, Fatty Acids, Unsaturated, Pycnanthuquinone B, Naphthoquinones |
| الوصف: | Two new compounds, pycnanthuquinone A (1) and pycnanthuquinone B (2), were isolated from leaves and stems of the African plant, Pycnanthus angolensis (Welw.) Warb (Myristicaceae), by bioassay-guided fractionation of an ethanolic extract using a diabetic mouse model. Pycnanthuquinones A and B are the first representatives of a novel terpenoid-type quinone skeleton, and both compounds possess significant antihyperglycemic activity. |
| تدمد: | 1520-6904 0022-3263 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075658656bed46c6716241f6f7d0eaef https://doi.org/10.1021/jo000568q |
| رقم الأكسشن: | edsair.doi.dedup.....075658656bed46c6716241f6f7d0eaef |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15206904 00223263 |
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