Report on the Relative Affinity Constant (M) of Hemoglobin for Carbon Monoxide in the Animal World: A Comparative Review with a Meta-Analysis Based on a Systematic Review
| العنوان: | Report on the Relative Affinity Constant (M) of Hemoglobin for Carbon Monoxide in the Animal World: A Comparative Review with a Meta-Analysis Based on a Systematic Review |
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| المؤلفون: | P M Roy, Ph. Hantson, Bruno Mégarbane, Giuseppe Liistro, Frédéric Thys, A Penaloza, N. Delvau |
| المساهمون: | UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - (SLuc) Service des urgences, UCL - (SLuc) Service de soins intensifs, UCL - (SLuc) Service de pneumologie |
| المصدر: | Journal of Evolutionary Biochemistry and Physiology, Vol. 55, no.5, p. 348-364 (2019) |
| بيانات النشر: | Pleiades Publishing Ltd, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0301 basic medicine, Evolution, Physiology, Haldane constant, Biochemistry, Methemoglobin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Animal science, Behavior and Systematics, Individual data, Fetal hemoglobin, Animal hemoglobin, Carbon monoxide, Ecology, Evolution, Behavior and Systematics, Ecology, M constant, Relative affinity constant of hemoglobin, Affinity constant, 030104 developmental biology, Carboxyhemoglobin, chemistry, Homogeneous, Meta-analysis, Hemoglobin, 030217 neurology & neurosurgery |
| الوصف: | The Haldane M-value is the ratio of half-saturation pressures for O2 and CO (PO2/PCO) and is a key value of physiological and pathological models exploring CO metabolism or exposure to CO. Nevertheless, the M-values obtained from different studies and different species appear to be inconsistent. A better estimation of M-values and a consideration of interspecies variation will ensure the accuracy of CO study results and allow reliable models to be constructed. We performed a systematic review and meta-analysis in order to determine and compare M-values according to species and experimental conditions. We used electronic libraries (PubMed/Embase/JSTORE) from 1895 to January 2016. For each article, we collected the following parameters: species, age, temperature, pH, atmospheric pressure, concentration of 2,3-diphosphoglycerate (2,3-DPG) or methemoglobin, and type of hemoglobin. The systematic review found 25 articles addressing the M constant, including 135 with individual data and 51 with mean values concerning mammals, laboratory animals, fish, fetal hemoglobin and invertebrates. M-values at a physiological temperature and pH were assessed only for adult (137 [119–153]) and fetal (135 [112–168]) sheep, dogs (215 [193–218]), mice (194 [118–278]) and rats (191 [177–200]). A correlation between M-values and temperature was confirmed for sheep and horses. A correlation between M-values and pH could not be inferred because there was a lack of data. M-values varied according to species. Only the influence of temperature was confirmed. A formal measurement of the M constant in the given experimental conditions should be performed for each animal model study of CO. Further homogeneous studies are necessary to compare the M-values of different animals. |
| تدمد: | 1608-3202 0022-0930 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079d1bda133d03383eb06f041edd5fb0 https://doi.org/10.1134/s0022093019050028 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....079d1bda133d03383eb06f041edd5fb0 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16083202 00220930 |
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