Advances in Liver Transplantation for Persons with Human Immunodeficiency Infection
العنوان: | Advances in Liver Transplantation for Persons with Human Immunodeficiency Infection |
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المؤلفون: | Rebecca N. Kumar, Valentina Stosor |
المصدر: | Current Infectious Disease Reports. 24:39-50 |
بيانات النشر: | Springer Science and Business Media LLC, 2022. |
سنة النشر: | 2022 |
مصطلحات موضوعية: | Infectious Diseases |
الوصف: | Advanced liver disease is a leading cause of non-AIDS-related morbidity and mortality in persons with HIV on antiretroviral therapy. As a result, persons with HIV are increasingly seeking liver transplantation.With the availability of direct-acting antiviral hepatitis C therapies, there has been a shift in the indications for liver transplantation in persons with HIV, with non-alcoholic fatty liver disease now the leading indication over hepatitis C infection. Additionally, liver transplant outcomes have improved in persons with HIV-hepatitis C co-infection persons with HIV. Preliminary results of HIV-to-HIV liver transplantation show acceptable results although rates of post-transplant infections and malignancies are areas of concern.Future studies of liver transplantation in persons with HIV should focus on long-term outcomes, especially in the context of steatohepatitis and co-existing morbidities like diabetes, hyperlipidemia, and cardiovascular disease and other prevalent diseases in an aging population. |
تدمد: | 1534-3146 1523-3847 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07feae757ca2c3590153605d69f74017 https://doi.org/10.1007/s11908-022-00776-3 |
حقوق: | CLOSED |
رقم الأكسشن: | edsair.doi.dedup.....07feae757ca2c3590153605d69f74017 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 15343146 15233847 |
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