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A novel method to demonstrate thrombus formation of the left atrial appendage in patients with persistent atrial fibrillation by cardiac computed tomography

التفاصيل البيبلوغرافية
العنوان: A novel method to demonstrate thrombus formation of the left atrial appendage in patients with persistent atrial fibrillation by cardiac computed tomography
المؤلفون: Yoshitaka Iwanaga, Tomoya Nagano, Yasuhito Kotake, Ryobun Yasuoka, Hiromi Yamamoto, Masahiro Maruyama, Gaku Nakazawa, Takashi Kurita, Motohide Tanaka, Yutaka Hirano
المصدر: International Journal of Cardiology. Heart & Vasculature
International Journal of Cardiology: Heart & Vasculature, Vol 36, Iss, Pp 100866-(2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
مصطلحات موضوعية: Cardiac computed tomography, medicine.medical_treatment, Left atrial appendage, Catheter ablation, Left atrial, Hounsfield scale, Diseases of the circulatory (Cardiovascular) system, Medicine, In patient, cardiovascular diseases, Thrombus, Transesophageal echocardiography, Original Paper, business.industry, Gold standard (test), medicine.disease, Algorithm, RC666-701, Persistent atrial fibrillation, cardiovascular system, Cardiology and Cardiovascular Medicine, business, Nuclear medicine
الوصف: Highlights • We created a new algorism to detect a left atrial appendage (LAA) thrombus on CT. • We measured HU density at one proximal (ostium) and seven distal sites of LAA. • A distal/proximal ratio and a standard deviation of HU density were analyzed by ROC. • Combination of the two parameters demonstrated a high accuracy for LAA thrombus.
Background Transesophageal echocardiography (TEE) is currently the gold standard technique for diagnosing left atrial appendage (LAA) thrombi. Cardiac computed tomography (CT) has been expected to become an alternative method to TEE; however, a reliable quantitative evaluation method has not been established. Methods and results We enrolled 177 patients with persistent atrial fibrillation who underwent both cardiac CT and TEE before catheter ablation. The patients were classified into two groups according to the TEE results: the thrombus group (13 patients) and non-thrombus group (164 patients). The Hounsfield unit (HU) density at the proximal LAA (LAAp) and distal LAA (LAAd) was measured on cardiac CT images. The LAAd/LAAp HU ratio and standard deviation of HU density (HU-SD) at the LAAd were evaluated. We created an algorithm by decision tree analysis to predict LAA thrombus formation using the HU ratio and HU-SD. Definite absence of LAA thrombus (Category-I) was diagnosed for 139 patients by combining the first and second branching of the decision tree (Category-Ia: HU ratio of ≥0.26, Category-Ib: HU ratio of
اللغة: English
تدمد: 2352-9067
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086023fd3df0e74886690b7dde25e14f
http://europepmc.org/articles/PMC8433278
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....086023fd3df0e74886690b7dde25e14f
قاعدة البيانات: OpenAIRE
الوصف
تدمد:23529067