α-Borylalkyl radicals: their distinctive reactivity in modern organic synthesis
| العنوان: | α-Borylalkyl radicals: their distinctive reactivity in modern organic synthesis |
|---|---|
| المؤلفون: | Ahmad Masarwa, Nivesh Kumar, Reddy Rajasekhar Reddy, Nadim Eghbarieh |
| المصدر: | Chemical Communications. 56:13-25 |
| بيانات النشر: | Royal Society of Chemistry (RSC), 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Radical, Metals and Alloys, Alkyl radicals, General Chemistry, Bond formation, 010402 general chemistry, 01 natural sciences, Combinatorial chemistry, Catalysis, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, chemistry.chemical_compound, Materials Chemistry, Ceramics and Composites, Moiety, Reactivity (chemistry), Organic synthesis, Alkyl |
| الوصف: | Organoborons are extremely important for synthetic organic chemistry; they can serve as advanced intermediates for a variety of transformations. Such a well-known transformation involves the loss of the boron moiety, creating alkyl radicals. Although these originally developed protocols for alkyl radical generation remain in active use today, in recent years their α-boryl carbon-centred radicals have been joined by a new array of radical generation strategies that offer a unique reactivity to forge a wider diversity of organoborons that often operate under mild and benign conditions. Herein, we will highlight the stability and reactivity of α-borylalkyl radicals and their remarkably recent advances in order to further utilise them for C-C and C-heteroatom bond formation. Their use for this purpose has been reported over the last decade in an attempt to guide the synthetic community. Various transition-metal and metal-free methods for their generation are presented, and more advanced photoredox approaches are discussed, mainly for the period of 2009-2019. |
| تدمد: | 1364-548X 1359-7345 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b80157c8045aa58aa8d91d46afd072 https://doi.org/10.1039/c9cc08027a |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....08b80157c8045aa58aa8d91d46afd072 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1364548X 13597345 |
|---|