Trichloroethylene Hypersensitivity Syndrome: A Disease of Fatal Outcome
| العنوان: | Trichloroethylene Hypersensitivity Syndrome: A Disease of Fatal Outcome |
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| المؤلفون: | Bong Gun Song, Eun Jin Kim, Hyun Gul Jung, Hyung Hun Kim |
| المصدر: | Yonsei Medical Journal |
| بيانات النشر: | Yonsei University College of Medicine, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Male, Resuscitation, Allergy, Case Report, Sepsis, sepsis, Fatal Outcome, medicine, Hypersensitivity, Humans, hepatitis, Asystole, Hepatitis, business.industry, General Medicine, Emergency department, occupational exposure, Jaundice, Middle Aged, medicine.disease, Trichloroethylene, Pneumonia, Dermatitis, Occupational, Anesthesia, Prednisolone, Solvents, medicine.symptom, business, medicine.drug |
| الوصف: | Trichloroethylene is commonly used as an industrial solvent and degreasing agent. The clinical features of acute and chronic intoxication with trichloroethylene are well-known and have been described in many reports, but hypersensitivity syndrome caused by trichloroethylene is rarely encountered. For managing patients with trichloroethylene hypersensitivity syndrome, avoiding trichloroethylene and initiating glucocorticoid have been generally accepted. Generally, glucocorticoid had been tapered as trichloroethylene hypersensitivity syndrome had ameliorated. However, we encountered a typical case of trichloroethylene hypersensitivity syndrome refractory to high dose glucocorticoid treatment. A 54-year-old Korean man developed jaundice, fever, red sore eyes, and generalized erythematous maculopapular rashes. A detailed history revealed occupational exposure to trichloroethylene. After starting intravenous methylprednisolone, his clinical condition improved remarkably, but we could not reduce prednisolone because his liver enzyme and total bilirubin began to rise within 2 days after reducing prednisolone under 60 mg/day. We recommended an extended admission for complete recovery, but the patient decided to leave the hospital against medical advice. The patient visited the emergency department due to pneumonia and developed asystole, which did not respond to resuscitation. |
| اللغة: | English |
| تدمد: | 1976-2437 0513-5796 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09262a34720b4fb1a1797b3eeb904ed7 http://europepmc.org/articles/PMC3250343 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....09262a34720b4fb1a1797b3eeb904ed7 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19762437 05135796 |
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