Complex Polysaccharide Inclusions in Skeletal Muscle Adjacent to Sarcomas in Two Dogs
| العنوان: | Complex Polysaccharide Inclusions in Skeletal Muscle Adjacent to Sarcomas in Two Dogs |
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| المؤلفون: | B. J. Cooper, Urs Giger, Beth A. Valentine, Robert J. Bildfell, Kay A. Fischer |
| المصدر: | Veterinary Pathology. 39:278-280 |
| بيانات النشر: | SAGE Publications, 2002. |
| سنة النشر: | 2002 |
| مصطلحات موضوعية: | 0301 basic medicine, Pathology, medicine.medical_specialty, 040301 veterinary sciences, Amylopectin, H&E stain, Stifle joint, Biology, 0403 veterinary science, Sarcoma, Synovial, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Polysaccharides, medicine, Animals, Dog Diseases, Muscle, Skeletal, Osteosarcoma, General Veterinary, Femoral Neoplasms, Skeletal muscle, 04 agricultural and veterinary sciences, Anatomy, medicine.disease, Stifle, Microscopy, Electron, 030104 developmental biology, medicine.anatomical_structure, Synovial Cell, chemistry, Cocker spaniel, Female, Sarcoma, Joint Diseases |
| الوصف: | Inclusions of periodic acid-Schiff-positive, amylase resistant material were found within skeletal muscle fibers adjacent to an osteosarcoma in the proximal femur of an 8-year-old intact female Cocker Spaniel dog (dog No. 1) and adjacent to a synovial cell sarcoma of the stifle joint in a 7-year-old spayed female Bouvier des Flandres dog (dog No. 2). Inclusions were pale blue-gray with hematoxylin and eosin stain and formed irregular inclusions, replacing up to approximately 80% of the fiber diameter. Inclusions from dog No. 2 were of non-membrane-bound granular to filamentous material that occasionally formed discrete, elongate electrondense masses. The features of these inclusions were similar to those of materials previously described as complex polysaccharide, polyglucosan bodies, amylopectin, and Lafora bodies. Evidence for a generalized metabolic disorder was not found in these two dogs, suggesting that storage of complex polysaccharide can occur as a relatively nonspecific response to metabolic alterations in skeletal muscle in a variety of conditions. |
| تدمد: | 1544-2217 0300-9858 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9057ff9920f13e4dfee6b846752428 https://doi.org/10.1354/vp.39-2-278 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....0a9057ff9920f13e4dfee6b846752428 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15442217 03009858 |
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