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Comparison of endothelial function and sympathetic nervous system activity along the glucose continuum in individuals with differing metabolic risk profiles and low dietary sodium intake

التفاصيل البيبلوغرافية
العنوان: Comparison of endothelial function and sympathetic nervous system activity along the glucose continuum in individuals with differing metabolic risk profiles and low dietary sodium intake
المؤلفون: Gavin W. Lambert, Sara Baqar, Elif I Ekinci, Nora E. Straznicky, John Dixon, George Jerums, Elisabeth Lambert, Yee Wen Kong
المصدر: BMJ Open Diabetes Research & Care
سنة النشر: 2018
مصطلحات موضوعية: Male, Sympathetic nervous system, endocrine system diseases, Endocrinology, Diabetes and Metabolism, 030204 cardiovascular system & hematology, Urine sodium, endothelial dysfunction, Impaired glucose tolerance, 0302 clinical medicine, Risk Factors, cardiovascular disease, Endothelial dysfunction, Glucose tolerance test, medicine.diagnostic_test, Middle Aged, 3. Good health, medicine.anatomical_structure, Female, type 2 diabetes, medicine.medical_specialty, Cardiovascular and Metabolic Risk, Endothelium, Manometry, Sodium, chemistry.chemical_element, 030209 endocrinology & metabolism, 03 medical and health sciences, Internal medicine, Glucose Intolerance, medicine, pulse amplitude tonometry, Humans, Aged, microneurography, sympathetic nervous system, twenty four hour urinary sodium excretion, business.industry, nutritional and metabolic diseases, Sodium, Dietary, Glucose Tolerance Test, medicine.disease, Endocrinology, impaired glucose tolerance, chemistry, Diabetes Mellitus, Type 2, business, Low sodium
الوصف: Objective: Low sodium intake may trigger sympathetic nervous system (SNS) activation and endothelial dysfunction. Studies have not explored these associations along the glucose continuum. Accordingly, we compared endothelial function and SNS activity in individuals with low sodium intake and differing categories of metabolic risk along the glucose continuum. We hypothesized that low sodium intake is associated with (1) impairment of endothelial function and (2) higher SNS activity in individuals with higher metabolic risk. Research Design and Methods: In this prospective observational study, participants (n=54) with low sodium intake (single 24 hours urine sodium excretion
تدمد: 2052-4897
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cbca362d47f1acb97b817bd4d1a2b88
https://pubmed.ncbi.nlm.nih.gov/31114697
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....0cbca362d47f1acb97b817bd4d1a2b88
قاعدة البيانات: OpenAIRE
الوصف
تدمد:20524897