Synthesis of Optically Active Organofluorides by Ring Opening of Oxazolidinone-Fused Aziridines
| العنوان: | Synthesis of Optically Active Organofluorides by Ring Opening of Oxazolidinone-Fused Aziridines |
|---|---|
| المؤلفون: | Hung-Che Chen, Chi-Yun Liu, Venkatachalam Angamuthu, Wei-Chen Chen, Chi-Sheng Wen, Duen-Ren Hou |
| المصدر: | Organic Letters. 25:190-194 |
| بيانات النشر: | American Chemical Society (ACS), 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Organic Chemistry, Physical and Theoretical Chemistry, Biochemistry |
| الوصف: | A general method for synthesizing optically active, primary, secondary, and tertiary organofluorides was developed. This chiral pool synthesis utilized the skeleton of arabinose to generate diastereomerically pure 2-oxazolidinone-fused aziridines, which underwent ring opening with a fluoride anion. The adducts, polyoxygenated organofluorides, were useful precursors to various fluorinated compounds, such as fluorinated amino acids. |
| تدمد: | 1523-7052 1523-7060 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6696159387d805d885f6710939c328 https://doi.org/10.1021/acs.orglett.2c04042 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....0d6696159387d805d885f6710939c328 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15237052 15237060 |
|---|