Intestinal toxicity of deoxynivalenol is limited by supplementation with Lactobacillus plantarum JM113 and consequentially altered gut microbiota in broiler chickens
| العنوان: | Intestinal toxicity of deoxynivalenol is limited by supplementation with Lactobacillus plantarum JM113 and consequentially altered gut microbiota in broiler chickens |
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| المؤلفون: | Xiaojun Yang, Shengru Wu, Xin Yang, Fangshen Guo, Fang Yan, Yanli Liu, Yongle Duan, Fangyuan Wang |
| المصدر: | Journal of Animal Science and Biotechnology, Vol 9, Iss 1, Pp 1-13 (2018) Journal of Animal Science and Biotechnology |
| بيانات النشر: | BMC, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, mRNA sequencing, Gut microbiota, Gut flora, Biochemistry, digestive system, Intestinal absorption, Jejunum, 03 medical and health sciences, Lactobacillus, medicine, Food science, 16S rRNA gene sequencing, lcsh:SF1-1100, Lactobacillus plantarum JM113, lcsh:Veterinary medicine, biology, Research, Broiler, food and beverages, biology.organism_classification, Deoxynivalenol, 030104 developmental biology, medicine.anatomical_structure, MRNA Sequencing, Broiler chickens, lcsh:SF600-1100, Animal Science and Zoology, lcsh:Animal culture, Digestion, Lactobacillus plantarum, Food Science, Biotechnology |
| الوصف: | Background Limited research has focused on the effect of Lactobacillus on the intestinal toxicity of deoxynivalenol (DON). The present study was conducted to investigate the role of Lactobacillus plantarum (L. plantarum) JM113 in protecting against the intestinal toxicity caused by DON. Methods A total of 144 one-day-old healthy Arbor Acres broilers were randomly distributed into 3 treatments, including the CON (basal diet), the DON (extra 10 mg/kg deoxynivalenol), and the DL (extra 1 × 109 CFU/ kg L. plantarum JM113 based on DON group) treatments. The growth performance, organ indexes, intestinal morphology, pancreatic digestive enzymes, intestinal secreted immunoglobulin A (sIgA), jejunal transcriptome, and intestinal microbiota were evaluated. Results Compared with the CON and DL groups, the DON supplementation altered intestinal morphology, especially in duodenum and jejunum, where villi were shorter and crypts were deeper (P |
| اللغة: | English |
| تدمد: | 2049-1891 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddfda4e678e109dd56c0cf4a6e14fb7 http://link.springer.com/article/10.1186/s40104-018-0286-5 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0ddfda4e678e109dd56c0cf4a6e14fb7 |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 20491891 |
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