Developmental changes in the myocardial architecture of the chick
| العنوان: | Developmental changes in the myocardial architecture of the chick |
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| المؤلفون: | Tomas Pexieder, Norman Hu, Edward B. Clark, David Sedmera |
| المصدر: | The Anatomical Record. 248:421-432 |
| بيانات النشر: | Wiley, 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Fetus, Time Factors, Cardiac Jelly, Embryonic heart, Myocardium, Heart, Embryonic Stage, Chick Embryo, Anatomy, Biology, Agricultural and Biological Sciences (miscellaneous), medicine.anatomical_structure, Trabecular Meshwork, Ventricle, Trabecular Pattern, Microscopy, Electron, Scanning, medicine, Animals, Mantle (mollusc), Endocardium |
| الوصف: | Background: Numerous studies describing myocardial ar- chitecture have been performed on the adult heart but considerably fewer have been made during embryonic or fetal development. To serve as a basis for interspecies comparison of ventricular morphology, and as a referenceforstudyingtheeffectsofexperimentalperturbations,weexamined the development of chick throughout the entire incubation period. Methods: Chick hearts from stage 14 (day 2) to stage 46 (day 21) were perfusion-fixed, and sectioned in transverse, frontal and sagittal planes. The ventricular myocardial architecture was examined and photo- graphed in the scanning electron microscope. Results:At embryonic stage 16 and earlier, the smooth-walled heart loop had an outer myocardial mantle, cardiac jelly, and endocardium. From stage 18, there was an outer compact and inner trabeculated myocardium. Trabeculated myocardium could be subdivided into the outer (basal) portion adjacent to the compact layer and the central (luminal) part. The outer basal layer could be distinguished from the inner luminal by shorter andfiner trabeculae with small, round intertrabecular spaces. From stage 24, the patterns of trabeculae and intertrabecular spaces were ventricle- specific. Between stages 24 to 31, abundant trabeculations were present throughout both ventricular cavities. The trabeculae were initially radi- ally arranged, but later adopted a spiral course, which persisted in a simplified form into adulthood. Conclusions:Theventricularmyocardiumundergoesdistinctivemorpho- genesis, characterized by changes in trabecular patterning and orienta- tion. We speculate that the embryonic trabecular architecture reflects the directions of the main stresses. Unlike fetal and adult hearts, which rely mostly on the compact myocardial layer, the trabeculae play a crucial role in the contractile function of the embryonic heart. Anat. Rec. 248:421-432 |
| تدمد: | 1097-0185 0003-276X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de820ed9bedc6d7140014ec89c64d61 https://doi.org/10.1002/(sici)1097-0185(199707)248:3<421::aid-ar15>3.0.co;2-r |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0de820ed9bedc6d7140014ec89c64d61 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 10970185 0003276X |
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