Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol
| العنوان: | Low-motion fMRI data can be obtained in pediatric participants undergoing a 60-minute scan protocol |
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| المؤلفون: | Fred R. Volkmar, Scuddy Fontenelle, Katarzyna Chawarska, Deanna Macris, Diogo Fortes, Corey Horien, Kohrissa Joseph, Maureen Butler, Nicole Powell, Kelly Powell, Dustin Scheinost, Chaela Nutor, Kangjoo Lee, R. Todd Constable, Abigail S. Greene, James C. McPartland |
| المصدر: | Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020) Scientific Reports |
| بيانات النشر: | Nature Portfolio, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Adolescent, Computer science, Science, Functional magnetic resonance imaging, Paediatric research, Article, 050105 experimental psychology, Session (web analytics), Motion (physics), Task (project management), 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Text mining, Replication (statistics), medicine, Humans, 0501 psychology and cognitive sciences, Child, Reliability (statistics), Protocol (science), Multidisciplinary, medicine.diagnostic_test, business.industry, 05 social sciences, Magnetic Resonance Imaging, Medicine, Female, business, 030217 neurology & neurosurgery |
| الوصف: | Performing functional magnetic resonance imaging (fMRI) scans of children can be a difficult task, as participants tend to move while being scanned. Head motion represents a significant confound in fMRI connectivity analyses. One approach to limit motion has been to use shorter MRI protocols, though this reduces the reliability of results. Hence, there is a need to implement methods to achieve high-quality, low-motion data while not sacrificing data quantity. Here we show that by using a mock scan protocol prior to a scan, in conjunction with other in-scan steps (weighted blanket and incentive system), it is possible to achieve low-motion fMRI data in pediatric participants (age range: 7–17 years old) undergoing a 60 min MRI session. We also observe that motion is low during the MRI protocol in a separate replication group of participants, including some with autism spectrum disorder. Collectively, the results indicate it is possible to conduct long scan protocols in difficult-to-scan populations and still achieve high-quality data, thus potentially allowing more reliable fMRI findings. |
| اللغة: | English |
| تدمد: | 2045-2322 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4b0515397014a7dd99e47868138082 https://doaj.org/article/17456881c17f4329826410a4bae7873a |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....0e4b0515397014a7dd99e47868138082 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20452322 |
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