التفاصيل البيبلوغرافية
العنوان:
Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: A prospective test validation study
المؤلفون:
Irina Bancos , Angela E Taylor , Vasileios Chortis , Alice J Sitch , Carl Jenkinson , Caroline J Davidge-Pitts , Katharina Lang , Stylianos Tsagarakis , Magdalena Macech , Anna Riester , Timo Deutschbein , Ivana D Pupovac , Tina Kienitz , Alessandro Prete , Thomas G Papathomas , Lorna C Gilligan , Cristian Bancos , Giuseppe Reimondo , Magalie Haissaguerre , Ljiljana Marina , Marianne A Grytaas , Ahmed Sajwani , Katharina Langton , Hannah E Ivison , Cedric H L Shackleton , Dana Erickson , Miriam Asia , Sotiria Palimeri , Agnieszka Kondracka , Ariadni Spyroglou , Cristina L Ronchi , Bojana Simunov , Danae A Delivanis , Robert P Sutcliffe , Ioanna Tsirou , Tomasz Bednarczuk , Martin Reincke , Stephanie Burger-Stritt , Richard A Feelders , Letizia Canu , Harm R Haak , Graeme Eisenhofer , M Conall Dennedy , Grethe A Ueland , Miomira Ivovic , Antoine Tabarin , Massimo Terzolo , Marcus Quinkler , Darko Kastelan , Martin Fassnacht , Felix Beuschlein , Urszula Ambroziak , Dimitra A Vassiliadi , Michael W O'Reilly , William F Young , Michael Biehl , Jonathan J Deeks , Wiebke Arlt , Stephan Glöckner , Richard O. Sinnott , Anthony Stell , Maria C. Fragoso , Ivana D. Pupovac , Sarah Cazenave , Jérôme Bertherat , Rossella Libé , Christina Brugger , Stefanie Hahner , Matthias Kroiss , Cristina L. Ronchi , Dimitra A. Vassiliadi , Vittoria Basile , Elisa Ingargiola , Massimo Mannelli , Hester Ettaieb , Harm R. Haak , Thomas M. Kerkhofs , Richard A. Feelders , Johannes Hofland , Leo J. Hofland , Marianne A. Grytaas , Eystein S. Husebye , Grethe A. Ueland , Malgorzata Zawierucha , Isabel Paiva , M. Conall Dennedy , Mark Sherlock , Rachel K. Crowley , Jonathan J. Deeks , Alice J. Sitch , Lorna C. Giligan , Beverly A. Hughes , Hannah E. Ivison , Konstantinos Manolopoulos , Donna M. O'Neil , Michael W. O'Reilly , Thomas G. Papathomas , Cedric H.L. Shackleton , Angela E. Taylor , Robert P. Sutcliffe , Peter Guest , Kassiani Skordilis , Alice Chang , Caroline J. Davidge-Pitts , Danae A. Delivanis , Neena Natt , Todd B. Nippoldt , Melinda Thomas , William F. Young Jr.
المساهمون:
Intelligent Systems, Interne Geneeskunde, RS: CAPHRI - R1 - Ageing and Long-Term Care, Internal Medicine
المصدر:
Lancet Diabetes & Endocrinology, 8(9), 773-781. ELSEVIER SCIENCE INC
سنة النشر:
2020
مصطلحات موضوعية:
Adult , Male , medicine.medical_specialty , Endocrinology, Diabetes and Metabolism , Adrenal Gland Neoplasms , SOCIETY , 030209 endocrinology & metabolism , Urine , adrenal incidentaloma , steroid metabolomics, adrenocortical carcinoma , Malignancy , Article , Diagnosis, Differential , 03 medical and health sciences , 0302 clinical medicine , Endocrinology , Hounsfield scale , Diagnosis , Internal Medicine , Humans , Metabolomics , Medicine , Adrenocortical carcinoma , Prospective Studies , 030212 general & internal medicine , Prospective cohort study , Aged , MALIGNANCY , Incidental Findings , medicine.diagnostic_test , business.industry , Europe , Female , Follow-Up Studies , Middle Aged , Steroids , Triple test , MASS-SPECTROMETRY , 16. Peace & justice , medicine.disease , 6. Clean water , 3. Good health , PREVALENCE , Differential , Histopathology , Differential diagnosis , business , Nuclear medicine
الوصف:
Background: Cross-sectional imaging regularly results in incidental discovery of adrenal tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is hampered by poor specificity of imaging characteristics. We aimed to validate a urine steroid metabolomics approach, using steroid profiling as the diagnostic basis for ACC. Methods: We did a prospective multicentre study in adult participants (age ≥18 years) with newly diagnosed adrenal masses. We assessed the accuracy of diagnostic imaging strategies based on maximum tumour diameter (≥4 cm vs
وصف الملف:
application/pdf
اللغة:
English
تدمد:
2213-8587
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc96786135a6a07e4ed9ff5ff6dc4d1 https://research.rug.nl/en/publications/a745ba9d-e987-4000-9122-b16a644be121
حقوق:
OPEN
رقم الأكسشن:
edsair.doi.dedup.....0fc96786135a6a07e4ed9ff5ff6dc4d1
قاعدة البيانات:
OpenAIRE
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