Growth performance, selected blood biochemical parameters and body weights of pre-pubertal gilts fed diets supplemented with different doses of zearalenone (ZEN)

التفاصيل البيبلوغرافية
العنوان: Growth performance, selected blood biochemical parameters and body weights of pre-pubertal gilts fed diets supplemented with different doses of zearalenone (ZEN)
المؤلفون: Michał Dąbrowski, Justyna Szcześniewska, Anna Rykaczewska, Anita Wiśniewska, Łukasz Zielonka, Magdalena Gajęcka, Maciej Gajęcki
المصدر: Toxicon. 152:84-94
بيانات النشر: Elsevier BV, 2018.
سنة النشر: 2018
مصطلحات موضوعية: 0301 basic medicine, Swine, Bilirubin, Food Contamination, Biology, Toxicology, Placebo, 03 medical and health sciences, chemistry.chemical_compound, Animal science, Total cholesterol, Animals, Zearalenone, Biotransformation, Total protein, Body Weight, Low dose, 0402 animal and dairy science, 04 agricultural and veterinary sciences, Animal Feed, 040201 dairy & animal science, Diet, 030104 developmental biology, chemistry, Energy expenditure, Urea, Female
الوصف: The aim of this study was to determine whether exposure to low doses of zearalenone (ZEN) induces changes in the serum biochemical profile and body weights (BW). Pre-pubertal gilts (with BW of up to 14.5 kg) were administered ZEN in daily doses of 5 μg/kg BW (group 1, n = 15), 10 μg/kg BW (group 2, n = 15), 15 μg/kg BW (group 3, n = 15) or placebo (control group C, n = 15) throughout the experiment. Blood was sampled for analysis on 10 dates (at five-day intervals). Minor but statistically significant differences in the analysed serum biochemical parameters (ALT, AST, ALP, total cholesterol, total bilirubin, glucose, total protein, iron, BUN and urea) were observed in the studied groups. The biochemical parameters of the analysed gilts indicate that the maintenance of homeostasis and biotransformation of ZEN require considerable energy expenditure. Beginning on the fourth analytical date, BW gains were consistently higher in the experimental groups than in group C. The observed decrease in glucose and total protein levels can probably be attributed to higher BW gains and the ongoing ZEN biotransformation processes in the enterocytes and the liver.
تدمد: 0041-0101
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bf9d22077a8af2e0d569670a073140
https://doi.org/10.1016/j.toxicon.2018.07.013
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....10bf9d22077a8af2e0d569670a073140
قاعدة البيانات: OpenAIRE