Halogen-Mediated Cascade Cyclization Reaction of Aryldiynes to Indeno[1,2-c]chromene Derivatives
| العنوان: | Halogen-Mediated Cascade Cyclization Reaction of Aryldiynes to Indeno[1,2-c]chromene Derivatives |
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| المؤلفون: | Chin-Chau Chen, Hsing-Yin Chen, Man-Yun Wu, Ming-Jung Wu |
| المصدر: | The Journal of Organic Chemistry. 82:6071-6081 |
| بيانات النشر: | American Chemical Society (ACS), 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | inorganic chemicals, chemistry.chemical_classification, Sulfide, 010405 organic chemistry, Chemistry, Dimer, Organic Chemistry, Substituent, chemistry.chemical_element, 010402 general chemistry, Iodine, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, Halogen, Organic chemistry, Molecule |
| الوصف: | The halogen-mediated cyclization reaction of aryldiynes to produce halogenated indeno[1,2-c]chromene derivatives is described. Treatment of aryldiynes 1 with one equivalent of iodine gave iodinated indeno[1,2-c]chromenes 3 in good chemical yields. When two equivalents of iodine were employed into the reaction mixture, dimer 9 was obtained as the major products. On the other hand, reaction of two equivalents of CuBr2 with compounds 1 gave the brominated indeno[1,2-c]chromenes 4. The DFT calculation of the iodine-mediated cyclization reactions for molecules containing methoxy, carboxy, amino, and sulfide substituents were carried out in order to understand how the substituent affects the cyclization pathway. |
| تدمد: | 1520-6904 0022-3263 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1101f7b0efcaaee6e851f90fb36ac664 https://doi.org/10.1021/acs.joc.7b00538 |
| رقم الأكسشن: | edsair.doi.dedup.....1101f7b0efcaaee6e851f90fb36ac664 |
| قاعدة البيانات: | OpenAIRE |
Find this issue from the American Chemical Society | تدمد: | 15206904 00223263 |
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